DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klp3A and si:cabz01066312.1

DIOPT Version :9

Sequence 1:	NP_001284830.1	Gene:	Klp3A / 31240	FlyBaseID:	FBgn0011606	Length:	1212	Species:	Drosophila melanogaster
Sequence 2:	XP_003198627.2	Gene:	si:cabz01066312.1 / 100537698	ZFINID:	ZDB-GENE-161017-136	Length:	488	Species:	Danio rerio

Alignment Length:	301	Identity:	63/301 - (20%)
Similarity:	113/301 - (37%)	Gaps:	77/301 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   842 QKVCPTDLDSRIRSLAEGVQSL-GESRTVSKQLLKTLVQQRRLQASSLNEQRTTLDELRAQLLDA 905
            :|.|          ||..:..| ||::..:|...:|..|...|.|.|.:.             ||
Zfish    29 EKCC----------LASDLMKLCGETKARNKARRRTTTQMELLYAHSGDP-------------DA 70

  Fly   906 QQQEDAASKRLRLLQSQHEEQML-----AQQRAYEEKVSVLIRTANQRWAEARSPAEDQQRNQIL 965
             ..||.:|..|.:::|....:.|     :..|....|::.:        :.||||...::::...
Zfish    71 -PPEDFSSPLLPVVESPEGNKELTPAPYSGDREPVTKINAV--------SSARSPTATERKSLDR 126

  Fly   966 EELLSSR--EALQQELDKLRAKNK----SKSKAVKSEPQDLDDSFQIVDGNETVVLS-DVSDDPD 1023
            ..|...|  |..|...|:.|..:|    |.:.|.:|..........:.:|:...:|. |.:||..
Zfish   127 SPLTRRRMQERSQNHTDRSRTLDKPGVASPALAARSSRAARLQCVHVAEGHTKPLLCLDSTDDLL 191

  Fly  1024 WVPSTSKSKRIQSDSRNVISPPEKQDANVTSLGN--SSIQSLNSTSA--------------TEDG 1072
            :..|..::.::.    |:::..|     :.|||:  ||:.|:...|:              ..|.
Zfish   192 FTGSKDRTCKVW----NLVTGQE-----IMSLGDHPSSVVSVRYCSSLVFTVSTAYVKVWDIRDS 247

  Fly  1073 KRCKGCKCRTKCTTKRCGCLSGNNACSETCVCKSNCRNPLN 1113
            .:|    .||..::   |.:|..:||..:.|......|.:|
Zfish   248 AKC----IRTLTSS---GQVSQGDACGGSAVAIPPGENQIN 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_001284830.1	KISc_KIF4	7..336	CDD:276823
		Kinesin	14..335	CDD:278646
		Smc	<396..>994	CDD:224117	36/163 (22%)
		FlaC	522..633	CDD:225888
		TCR	1075..1110	CDD:281618	8/34 (24%)
si:cabz01066312.1	XP_003198627.2	WD40	170..478	CDD:238121	26/128 (20%)
		WD40	176..>480	CDD:225201	26/122 (21%)
		WD40 repeat	222..256	CDD:293791	6/37 (16%)
		WD40 repeat	280..319	CDD:293791	1/2 (50%)
		WD40 repeat	324..360	CDD:293791
		WD40 repeat	367..407	CDD:293791
		WD40 repeat	413..446	CDD:293791
		WD40 repeat	455..477	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D74122at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010