DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13760 and gucd1

DIOPT Version :9

Sequence 1:	NP_570010.3	Gene:	CG13760 / 31237	FlyBaseID:	FBgn0040375	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001070630.1	Gene:	gucd1 / 564677	ZFINID:	ZDB-GENE-060929-872	Length:	226	Species:	Danio rerio

Alignment Length:	228	Identity:	88/228 - (38%)
Similarity:	128/228 - (56%)	Gaps:	15/228 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NLTHYQQRYNWDCGLSCIIMILS----AQQREQLLGNFDAVCGEEGFGSSTWTIDLCYLLMRYQV 71
            |:...:|.|:|||||:|..|:|.    ..:.|     |...|.:..|..|.|||||.||:.:..|
Zfish     8 NVPVIRQLYHWDCGLACSRMVLEYLNPVSEEE-----FQRACMDLEFTESVWTIDLAYLMCKLGV 67

  Fly    72 RHEYFTQTLGIDPNYAQHTYYSKIIDKDERRVTRKFKDARAHGLRVEQRTVDMEVILRHLARHGP 136
            ||.:.|||||:|..:...::|.|..|.:|.||...|..|.:.|:.|::.:|.::.|..||.:...
Zfish    68 RHCFCTQTLGVDKGFRNQSFYKKHFDTEEDRVNELFLKAESKGVLVKKCSVTVQEIQSHLEQGHV 132

  Fly   137 VILLTNASLLTCEVCKRNVLEKFGCFHIPCIAQNTRLHGPKRYAGHYVVLCGYDMAAQKLFYHNP 201
            .|:|.||.||.||:|...|  |:.|| :| :.|......|. |.||:||:||::.....:||:||
Zfish   133 AIVLVNAVLLVCELCSTPV--KYCCF-LP-VGQKCFCRKPD-YQGHFVVVCGFNRKTSSIFYNNP 192

  Fly   202 EVHDGHICRCLIESMDTARRAYGTDEDIIFIYE 234
            ...| .:|.....:.:.|||:|||||||:|||:
Zfish   193 AYSD-RVCCTSFSNFEEARRSYGTDEDILFIYK 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13760	NP_570010.3	Guanylate_cyc_2	12..232	CDD:286819	84/223 (38%)
gucd1	NP_001070630.1	Guanylate_cyc_2	9..222	CDD:286819	84/223 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574077
Domainoid	1	1.000	153	1.000	Domainoid score	I4269
eggNOG	1	0.900	-	-		E1_KOG4621
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57149
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4242
OMA	1	1.010	-	-		QHG59989
OrthoDB	1	1.010	-	-		D1348354at2759
OrthoFinder	1	1.000	-	-		FOG0007340
OrthoInspector	1	1.000	-	-		oto41421
orthoMCL	1	0.900	-	-		OOG6_106070
Panther	1	1.100	-	-	LDO	PTHR31400
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5856
SonicParanoid	1	1.000	-	-		X5456
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800