DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha36-3 and Atp6v1d

DIOPT Version :9

Sequence 1:	NP_001284828.1	Gene:	Vha36-3 / 31235	FlyBaseID:	FBgn0040377	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_076210.1	Gene:	Atp6v1d / 73834	MGIID:	1921084	Length:	247	Species:	Mus musculus

Alignment Length:	249	Identity:	171/249 - (68%)
Similarity:	200/249 - (80%)	Gaps:	3/249 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAKDRLPIFPSRGAQTLMKSRLAGATKGHGLLKKKADALQMRFRLILGKIIETKTLMGQVMKEA 65
            |:.|||:.|||||.|||:||:||.||..|..|||||:|||.:|||.||.||||||.|||:||:||
Mouse     1 MSGKDRIEIFPSRMAQTIMKARLKGAQTGRNLLKKKSDALTLRFRQILKKIIETKMLMGEVMREA 65

  Fly    66 AFSLAEVKFTTGDINQIVLQNVTKAQIKIRTKKDNVAGVTLPIFEPYTDGVDTYELAGLARGGQQ 130
            ||||||.|||.||.:..|:|||.|||:|||.|||||||||||:||.|.:|.|:|||.||||||:|
Mouse    66 AFSLAEAKFTAGDFSTTVIQNVNKAQVKIRAKKDNVAGVTLPVFEHYHEGTDSYELTGLARGGEQ 130

  Fly   131 LAKLKKNYQSAVRLLVQLASLQTSFVTLDDVIKVTNRRVNAIEHVIIPRINRTIEYIISELDELE 195
            |||||:||..||.|||:||||||||||||:.||:||||||||||||||||.||:.|||:||||.|
Mouse   131 LAKLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPRIERTLAYIITELDERE 195

  Fly   196 REEFYRLKKIQDKKREARKASDKLRAEQRLLGQMAEAQEVQNILDEDGDEDLLF 249
            |||||||||||:||:..::..:|....:|..|   |..|..|:|.|:.||||||
Mouse   196 REEFYRLKKIQEKKKIIKEKFEKDLERRRAAG---EVMEPANLLAEEKDEDLLF 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha36-3	NP_001284828.1	ATP-synt_D	17..206	CDD:280060	142/188 (76%)
Atp6v1d	NP_076210.1	ATP-synt_D	17..202	CDD:396399	138/184 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849892
Domainoid	1	1.000	296	1.000	Domainoid score	I1469
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2381
Isobase	1	0.950	-	0	Normalized mean entropy	S324
OMA	1	1.010	-	-		QHG60833
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003389
OrthoInspector	1	1.000	-	-		otm42929
orthoMCL	1	0.900	-	-		OOG6_101069
Panther	1	1.100	-	-	O	PTHR11671
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1631
SonicParanoid	1	1.000	-	-		X2286
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.880