DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha36-3 and atp6v1d

DIOPT Version :9

Sequence 1:	NP_001284828.1	Gene:	Vha36-3 / 31235	FlyBaseID:	FBgn0040377	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001161426.1	Gene:	atp6v1d / 393935	ZFINID:	ZDB-GENE-040426-727	Length:	248	Species:	Danio rerio

Alignment Length:	250	Identity:	170/250 - (68%)
Similarity:	205/250 - (82%)	Gaps:	4/250 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAKDRLPIFPSRGAQTLMKSRLAGATKGHGLLKKKADALQMRFRLILGKIIETKTLMGQVMKEA 65
            |:.|:|:.|||||.|||:||:||.||..|..|||||:|||.||||.||.||||||||||:||:||
Zfish     1 MSGKERIDIFPSRMAQTIMKARLKGAQTGRSLLKKKSDALSMRFRQILRKIIETKTLMGEVMREA 65

  Fly    66 AFSLAEVKFTTGDINQIVLQNVTKAQIKIRTKKDNVAGVTLPIFEPYTDGVDTYELAGLARGGQQ 130
            ||||||.||..||.:..|:|||.|||:|:|.|||||||||||:||.|.:|.|:|||.||||||:|
Zfish    66 AFSLAEAKFAAGDFSTTVIQNVNKAQVKVRAKKDNVAGVTLPVFEHYQEGGDSYELTGLARGGEQ 130

  Fly   131 LAKLKKNYQSAVRLLVQLASLQTSFVTLDDVIKVTNRRVNAIEHVIIPRINRTIEYIISELDELE 195
            |::||:||..||.|||:||||||||||||:.||:||||||||||||||||.||:.|||:||||.|
Zfish   131 LSRLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPRIERTLTYIITELDERE 195

  Fly   196 REEFYRLKKIQDKKREARKASDKLRAEQ-RLLGQMAEAQEVQNILDEDGDEDLLF 249
            |||||||||||:||::.|:.::|..|:: ..||.:||.   .|:|.|:.||||||
Zfish   196 REEFYRLKKIQEKKKQLRERTEKEIAKRLAALGPIAEP---TNMLTEEADEDLLF 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha36-3	NP_001284828.1	ATP-synt_D	17..206	CDD:280060	140/188 (74%)
atp6v1d	NP_001161426.1	ATP-synt_D	17..206	CDD:280060	140/188 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595705
Domainoid	1	1.000	295	1.000	Domainoid score	I1462
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2371
OMA	1	1.010	-	-		QHG60833
OrthoDB	1	1.010	-	-		D1313938at2759
OrthoFinder	1	1.000	-	-		FOG0003389
OrthoInspector	1	1.000	-	-		otm26092
orthoMCL	1	0.900	-	-		OOG6_101069
Panther	1	1.100	-	-	O	PTHR11671
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1631
SonicParanoid	1	1.000	-	-		X2286
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940