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Protein Alignment Pdfr and ADGRE3

DIOPT Version :10

Sequence 1:	NP_001245501.1	Gene:	Pdfr / 31234	FlyBaseID:	FBgn0260753	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_115960.2	Gene:	ADGRE3 / 84658	HGNCID:	23647	Length:	652	Species:	Homo sapiens

Alignment Length:	343	Identity:	81/343 - (23%)
Similarity:	139/343 - (40%)	Gaps:	67/343 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 LMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVL 354
            ::..:.|::.|..:.:      :..|||.:||..|:::.|.|...:::||..|.:|..|.:.:.|
Human   343 VLMALTSQEEDPVLTV------ITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFL 401

  Fly   355 QVIIRLTLYLDQFRRGNKEAATNTSLSVIENTP-YLCEASYVLLEYARTAMFMWMFIEGLYLH-- 416
            ..::.|                   :.:....| .||......|.|...|.|.||.:||::|.
Human   402 AHLLFL-------------------VGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLT 447

  Fly   417 -NMVTVAVFQG--------SFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNYNLTPY 472
             ..:||..:..        .||      :|:.||.:...:.| .:..::..:...| |.:....:
Human   448 ARNLTVVNYSSINRLMKWIMFP------VGYGVPAVTVAISA-ASWPHLYGTADRC-WLHLDQGF 504

  Fly   473 YWILEGPRLAVILLNFCFLVNIIRVLVMKLR--QSQASDIEQTRKAVRAAIVLLPLLGIT---NL 532
            .|...||..|:...|....:.:..:|..||.  .|:.|.|:.||.....|...|.:||.|   .|
Human   505 MWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGL 569

  Fly   533 LHQLAPLKTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEVR-------AVLLKSLATQ----L 586
            | |:.|..     .|.:|....:.|.|||||.|:||.|:.:|:       ..::||.:..    |
Human   570 L-QVGPAA-----QVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTL 628

  Fly   587 SVRGHPEWAPKRASMYSG 604
            |.:..|:..|....::.|
Human   629 SSKMGPDSKPSEGDVFPG 646

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.