Protein Alignment Pdfr and ghrhrb

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_001331921.5
• Gene: ghrhrb / 792410
• ZFINID: ZDB-GENE-110127-2
• Length: 453
• Species: Danio rerio
• Alignment Length: 405
• Identity: 104/405 - (25%)
• Similarity: 179/405 - (44%)
• Gaps: 59/405 - (14%)

  Fly   212 TGLYCNWTWDTLLCWPPTPAGVLARMNCPGGFHGVDTRKFAIRKCELDGRWGSRPNATEVNPPGW 276
            ||  |...||...||.....|.:..::|...........|..|.|..|               ||
Zfish    64 TG--CPTEWDEFWCWSGAEVGQVVNISCSEVSQLFVNHGFIFRNCTKD---------------GW 111

  Fly   277 TDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNR 341
            |:..|.|: ....:::.:.|:....|....|:..|   .|...||.:||.::.:|..||.....|
Zfish   112 TEVYPSYE-NACEIVEDVESETETTYYATFRQVYT---AGYATSLISLITAIFVFTVFRKFHCTR 172

  Fly   342 TKIHKNLFVAMVLQ---VIIR-LTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYART 402
            ..||.|||.:.:|:   :.|: ..|:.|:          |.....:..|.  |:|:....:::..
Zfish   173 NYIHINLFASFILRASAIFIKDAVLFADE----------NLDHCFMSTTS--CKAAVAFFQFSIL 225

  Fly   403 AMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNY 467
            |.:.|:.:||:||..::.:..........::..:||.:|.|:.|:|......:.:..   |..:.
Zfish   226 ANYFWLLVEGMYLQTLLALTFVSQKKYFWWYILIGWGLPTLILTIWVLARNFFDNNG---CWDDT 287

  Fly   468 NLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQ--SQASDIEQTRKAVRAAIVLLPLLGIT 530
            ::..::||::||....:|:||...:|:||:||.||:.  ....|.....:..::.:.|:||.|:.
Zfish   288 DVAYFWWIIKGPITVSLLINFLIFINVIRILVQKLKSPGMGGGDTNHFMRLAKSTLFLIPLFGMH 352

  Fly   531 NLLHQLAPLKTATNFAVWSYGTHFLT----SFQGFFIALIYCFLNGEVRAVLLKSL---ATQLSV 588
            .::....|..|..|      ..|||.    .||||.:||:||||||||:|.|.|.|   .||..:
Zfish   353 YMVFAFLPENTGEN------ARHFLELGLGPFQGFVVALLYCFLNGEVQAELKKRLWKWQTQSYL 411

  Fly   589 RGHPEWAPKRASMYS 603
            |    ::.:|.::::
Zfish   412 R----YSKRRRTLFT 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	12/58 (21%)
		7tmB1_PDFR	306..584	CDD:320389	80/290 (28%)
		TM helix 1	308..333	CDD:320389	7/24 (29%)
		TM helix 2	342..364	CDD:320389	8/25 (32%)
		TM helix 3	391..418	CDD:320389	7/26 (27%)
		TM helix 4	430..450	CDD:320389	6/19 (32%)
		TM helix 5	469..498	CDD:320389	10/28 (36%)
		TM helix 6	512..539	CDD:320389	4/26 (15%)
		TM helix 7	546..571	CDD:320389	12/28 (43%)
ghrhrb	XP_001331921.5	HRM	65..123	CDD:397086	17/75 (23%)
		7tmB1_GHRHR2	137..404	CDD:320399	80/290 (28%)
		TM helix 1	139..164	CDD:320399	8/27 (30%)
		TM helix 2	173..195	CDD:320399	7/21 (33%)
		TM helix 3	214..241	CDD:320399	7/26 (27%)
		TM helix 4	253..273	CDD:320399	6/19 (32%)
		TM helix 5	288..318	CDD:320399	10/29 (34%)
		TM helix 6	334..361	CDD:320399	4/26 (15%)
		TM helix 7	366..391	CDD:320399	13/30 (43%)