Protein Alignment Pdfr and Crhr1

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_063125810.1
• Gene: Crhr1 / 58959
• RGDID: 61276
• Length: 452
• Species: Rattus norvegicus
• Alignment Length: 475
• Identity: 151/475 - (31%)
• Similarity: 214/475 - (45%)
• Gaps: 98/475 - (20%)

  Fly   157 LALEPTVMDALPDSDTEQVLGNLNSSAPWNLTLASAAATNFENCSALFVNYTLPQTGLYCNWTWD 221
            |.|.| |..:|.|...|            ||:|.|       |.|           ||.||.:.|
  Rat    53 LGLNP-VSTSLQDQRCE------------NLSLTS-------NVS-----------GLQCNASVD 86

  Fly   222 TL-LCWPPTPAGVLARMNCPGGFHGV--DTRKFAIRKCELDGRWGSRPNATEVNPPGWTDYGPCY 283
            .: .|||.:|||.|....||..|:||  :|.....|:|..:|.|.:|.|           |..|
  Rat    87 LIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVN-----------YSEC- 139

  Fly   284 KPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNL 348
             .||  |.::..||   .:..:|   ..:..:|.|:||.||:|:.::|...||:|..|..||.||
  Rat   140 -QEI--LNEEKKSK---VHYHVA---VIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNL 195

  Fly   349 FVAMVLQ----VIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMF 409
            ..|.:|:    .:::||:                |..|.::....|........|.....|.|||
  Rat   196 ISAFILRNATWFVVQLTV----------------SPEVHQSNVAWCRLVTAAYNYFHVTNFFWMF 244

  Fly   410 IEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNYNLTPYY- 473
            .||.|||..:.:...........|..:||.||..:...||...:.|.:    |..|.......|
  Rat   245 GEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDN----EKCWFGKRPGVYT 305

  Fly   474 -WILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQASDIEQTRKAVRAAIVLLPLLGITNLLHQLA 537
             :|.:||.:.|:|:||.||.||:|:|:.|||.|..|:..|.||||:|.:|||||||||.:|..:.
  Rat   306 DYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVN 370

  Fly   538 PLKTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEVRAVLLK-------------SLATQLSVR 589
            |.:...:..|:.|...||.||||||:::.|||||.|||:.:.|             .:|..:|:
  Rat   371 PGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSI- 434

  Fly   590 GHPEWAPKRASMYSGAYNTA 609
               ..:|.|.|.:|...:||
  Rat   435 ---PTSPTRVSFHSIKQSTA 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	24/61 (39%)
		7tmB1_PDFR	306..584	CDD:320389	99/296 (33%)
		TM helix 1	308..333	CDD:320389	8/24 (33%)
		TM helix 2	342..364	CDD:320389	8/25 (32%)
		TM helix 3	391..418	CDD:320389	10/26 (38%)
		TM helix 4	430..450	CDD:320389	6/19 (32%)
		TM helix 5	469..498	CDD:320389	13/30 (43%)
		TM helix 6	512..539	CDD:320389	16/26 (62%)
		TM helix 7	546..571	CDD:320389	13/24 (54%)
Crhr1	XP_063125810.1	None