Protein Alignment Pdfr and PTH1R

DIOPT Version :9

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_011532269.1
• Gene: PTH1R / 5745
• HGNCID: 9608
• Length: 606
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 137/485 - (28%)
• Similarity: 207/485 - (42%)
• Gaps: 96/485 - (19%)

  Fly   213 GLYCNWTWDTLLCWPPTPAGVLARMNCPGGFHGVDTRKFAIRKCELDGRWGSRP--NATEVNPPG 275
            |..|...||.:||||....|.:..:.||...:..:.:..|.|:|:.:|.|...|  |.|
Human   118 GRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRT------ 176

  Fly   276 WTDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEI---------VGLCLSLFALIVSLLIF 331
            |.:|..|.|                   .:...||..|:         ||..:||.:|.|::||.
Human   177 WANYSECVK-------------------FLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLIL 222

  Fly   332 CTFRSLRNNRTKIHKNLFVAMVLQVII----RLTLY----LDQFRRGNKEAATNTSLSVIENTP- 387
            ..||.|...|..||.:||::.:|:.:.    ...||    ||:     .|..|...|..|...|
Human   223 AYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDE-----AERLTEEELRAIAQAPP 282

  Fly   388 --------YL-CEASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPIL 443
                    |. |..:.....|.....:.|:.:||||||:::.:|.|.....|..|:..||.:|.:
Human   283 PPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAV 347

  Fly   444 MTTVWARCTVMYMDTSLGECLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQAS 508
            ...||........:|.   | |:.:.....||::.|.||.|:|||...:||:|||..|||::.|.
Human   348 FVAVWVSVRATLANTG---C-WDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAG 408

  Fly   509 DI---EQTRKAVRAAIVLLPLLGITNLLHQLAPLKTATNFAVWSYGTHF---LTSFQGFFIALIY 567
            ..   :|.||.:::.:||:||.|:..::....|. |..:..:|....|:   ..||||||:|:||
Human   409 RCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPY-TEVSGTLWQVQMHYEMLFNSFQGFFVAIIY 472

  Fly   568 CFLNGEVRAVLLKSLATQLSVRGHPEWA-----PKRASMYSGAYNTAP--DTDAVQPAGDPSATG 625
            ||.||||:|.:.||.:         .|.     .::|...|.:|:..|  ...:|...|.....|
Human   473 CFCNGEVQAEIKKSWS---------RWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLG 528

  Fly   626 KRISP---PNKRLNGR-------KPSSASI 645
            ..:||   |....||.       ||.:.::
Human   529 LPLSPRLLPTATTNGHPQLPGHAKPGTPAL 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:280888	19/60 (32%)
		7tm_4	306..563	CDD:304433	86/289 (30%)
PTH1R	XP_011532269.1	HRM	118..186	CDD:280888	23/92 (25%)
		7tm_2	197..468	CDD:278432	83/280 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290902at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45620
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020