Protein Alignment Pdfr and gcgrb

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_073763206.1
• Gene: gcgrb / 565237
• ZFINID: ZDB-GENE-050516-2
• Length: 509
• Species: Danio rerio
• Alignment Length: 522
• Identity: 144/522 - (27%)
• Similarity: 225/522 - (43%)
• Gaps: 115/522 - (22%)

  Fly   195 TNFENCSALFVNYTLPQTGLYCNWTWDTLLCWPPTPAGVLARMNCPGGF-------HGVDTRKFA 252
            ||  .|...|:: |.|..||.||.|:|..:|||....|....::||...       ||:     .
Zfish    35 TN--ECIQSFIS-TPPAAGLVCNRTFDQYVCWPDGLPGTTVNVSCPWYLPWYSKVDHGL-----V 91

  Fly   253 IRKCELDGRW--GSRPNATEVNPPGWTDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIV 315
            .|.|..||||  |...:..|.:.||...||                       .|..:.|.:..|
Zfish    92 YRVCGADGRWVHGKNTSECEQDDPGQKQYG-----------------------QILSKFRAMYTV 133

  Fly   316 GLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNL---FVAMVLQVIIRLTLYLDQFRRGNKEAATN 377
            |..|||.||.::|.|..:||.|...|..||.||   |:...|.::|:.|| |||..|      ..
Zfish   134 GYSLSLAALTLALGILVSFRKLHCMRNNIHMNLFGSFMVRALSILIKDTL-LDQMNR------AR 191

  Fly   378 TSLSVIENTPYL-------CEASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSR 435
            :..|..::|.:|       |.::.|:::|:..|...|:.:||||||:::...||........:..
Zfish   192 SGPSHYQSTRWLDTQTVVGCRSAMVMMQYSVMANNCWLLVEGLYLHSLLVTTVFSERNYFCIYLC 256

  Fly   436 LGWCVPILMTTVWARCTVMYMDTSLGECLWNYNLT-PYYWILEGPRLAVILLNFCFLVNIIRVLV 499
            :||..|::....|.....:|.:.   || |..|:. .|:||:..|.|...|:||...:.||::|:
Zfish   257 IGWGAPLIFVLPWMTVKYLYENE---EC-WERNMNMGYWWIIRSPILFAYLINFIIFIRIIKILM 317

  Fly   500 MKLRQSQASDIEQTRKAVRAAIVLLPLLGI-----TNLLHQLAPLKTATNFAVWSYGTHFLTSFQ 559
            .||:..|....:...:..::.:.|:|||||     |.::.:..|.::........|...| :|||
Zfish   318 SKLKAHQMRYTDYKFRLAKSTLTLIPLLGIHAVLFTFVIDESVPKESLLRLIRLFYDLLF-SSFQ 381

  Fly   560 GFFIALIYCFLNGEVRAVLLKSLATQLSVRGHPEWAPKRASMYSGAYNTAPDTDAVQPAGDPSAT 624
            |..:|::|||:|.||::.:||            :|  ||..:
Zfish   382 GLLVAILYCFVNKEVQSEMLK------------KW--KRWKL----------------------- 409

  Fly   625 GKRISPPNKRLNGRKP---SSASIVMIHE-PQ-----QRQRLMPRLQN-KAREKGKDRVEKTDAE 679
            ||.|....:..:.:.|   ||.:....|: |.     :.|||:..||| .:|.:|:.|::.|...
Zfish   410 GKDIDEEYRHTHSQTPHAKSSTAPPAAHDCPDTSSSLESQRLVTGLQNGLSRSRGRARLQFTSQT 474

  Fly   680 AE 681
            .|
Zfish   475 QE 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	22/67 (33%)
		7tmB1_PDFR	306..584	CDD:320389	89/293 (30%)
		TM helix 1	308..333	CDD:320389	10/24 (42%)
		TM helix 2	342..364	CDD:320389	9/24 (38%)
		TM helix 3	391..418	CDD:320389	10/26 (38%)
		TM helix 4	430..450	CDD:320389	4/19 (21%)
		TM helix 5	469..498	CDD:320389	10/29 (34%)
		TM helix 6	512..539	CDD:320389	7/31 (23%)
		TM helix 7	546..571	CDD:320389	10/24 (42%)
gcgrb	XP_073763206.1	None