Protein Alignment Pdfr and adcyap1r1a

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_073772877.1
• Gene: adcyap1r1a / 541315
• ZFINID: ZDB-GENE-050315-1
• Length: 486
• Species: Danio rerio
• Alignment Length: 512
• Identity: 132/512 - (25%)
• Similarity: 205/512 - (40%)
• Gaps: 129/512 - (25%)

  Fly   216 CNWTWDTLLCWPPTPAGVLARMNCPGGFHGVDTRKFAIRKCELDGRWGSRPNATEVNPPGWTDYG 280
            |.|.||.|.||.....|.:..:|||..|..:...         :|......|.||.   ||::..
Zfish    56 CPWEWDNLTCWQAASVGDVVEVNCPELFEFMSPE---------EGLGKISRNCTEF---GWSEPY 108

  Fly   281 PCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIH 345
            |.|   :...|....:...|.|.   ...:.|..||...||.:|..:::|.|.||.|...|..||
Zfish   109 PHY---VDACMTDENTTKPDMYY---ASVKALYTVGYSTSLVSLTTAMVILCRFRKLHCTRNFIH 167

  Fly   346 KNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMFI 410
            .||||:.:|:.|   ::::   :.|...|..::....:....  |:|..|...|...:.:.|:||
Zfish   168 MNLFVSFILRAI---SVFI---KDGVLYAEEDSDHCFVHTVG--CKAVMVFFHYCVMSNYFWLFI 224

  Fly   411 EGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNYN-LTPYYW 474
            |||||..::....|.......:::.:||..|.:..|:||...:.:.|:.   | |:.| .|..:|
Zfish   225 EGLYLFTLLVETFFPERRYFYWYTIIGWGTPTICVTIWAVLRLHFDDSG---C-WDMNDNTALWW 285

  Fly   475 ILEGPRLAVILLNFCFLVNIIRVLVMKL--------------------------------RQSQA 507
            :::||.:|.|::||...:.||.:||.||                                |.|:.
Zfish   286 VIKGPVVASIMINFVLFIGIIIILVQKLQSPDIGGNESSIYLSCAQKCFSEPTQAVQHSCRMSEL 350

  Fly   508 SDIEQTRKAVRAAIVLLPLLGITNLLHQLAPLKTATNFA-----VWSYGTHFLTSFQGFFIALIY 567
            |.|  |.:..|:.::|:||.||...:...:|    .:|:     |:..|   |.|||||.:|::|
Zfish   351 STI--TLRLARSTLLLIPLFGIHYTVFAFSP----EDFSKRERLVFELG---LGSFQGFVVAVLY 406

  Fly   568 CFLNGEVRAVLLKSLATQLSVRGHPEWAPKRASMYSGAYNTAP-----DTDAVQPAGDPSATGKR 627
            |||||                    |:.||      ||.....     |.:.|...|..:|.
Zfish   407 CFLNG--------------------EFLPK------GAVGDKEEMEELDGEQVLCCGPEAAA--- 442

  Fly   628 ISPPNKRLNGRKPSSASIVMIHEPQQRQRLMPRLQNKAREKGKDRVEKTDAEAEPDP 684
             ||......|.:..:|    :| |||.|.....:|...|            :::|.|
Zfish   443 -SPFASEQWGERGDAA----VH-PQQEQLSDTHVQPSGR------------DSQPQP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	16/55 (29%)
		7tmB1_PDFR	306..584	CDD:320389	87/315 (28%)
		TM helix 1	308..333	CDD:320389	7/24 (29%)
		TM helix 2	342..364	CDD:320389	8/21 (38%)
		TM helix 3	391..418	CDD:320389	11/26 (42%)
		TM helix 4	430..450	CDD:320389	5/19 (26%)
		TM helix 5	469..498	CDD:320389	10/28 (36%)
		TM helix 6	512..539	CDD:320389	7/26 (27%)
		TM helix 7	546..571	CDD:320389	12/29 (41%)
adcyap1r1a	XP_073772877.1	None