Protein Alignment Pdfr and Dh44-R1

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 482
• Identity: 139/482 - (28%)
• Similarity: 212/482 - (43%)
• Gaps: 79/482 - (16%)

  Fly   215 YCNWTWDTLLCWPPTPAGVLARMNCPGGFHGV--DTRKFAIRKCELDGRWGSRPNATEVNPPGWT 277
            :|...:|::||||.|..|.||.:.|.....|:  |:.|.|.|.|..:|.|..           :|
  Fly    52 HCLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSKNATRFCHANGTWEK-----------YT 105

  Fly   278 DYGPCY---KPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRN 339
            :|..|.   .||.:        .:|:..:::   ...:..:|..|||.:|.::|::|..|:.||.
  Fly   106 NYDACAHLPAPESV--------PEFEVIVEL---PTIIYYIGYTLSLVSLSLALIVFAYFKELRC 159

  Fly   340 NRTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSV---IENTPYLCEASYVLLEYAR 401
            .|..||.|||...::..:..:.|                 |||   |.:....|.|...|..:..
  Fly   160 LRNTIHANLFFTYIMSALFWILL-----------------LSVQISIRSGVGSCIALITLFHFFT 207

  Fly   402 TAMFMWMFIEGLYLHNMVTVAVFQGSFPLKF--FSRLGWCVPILMTTVWA---RCTVMYMDTSLG 461
            ...|.||.:|||||: |:.|..|.|. .|:|  ::.:||..|.|....||   ..||.|......
  Fly   208 LTNFFWMLVEGLYLY-MLVVKTFSGD-NLRFNIYASIGWGGPALFVVTWAVAKSLTVTYSTPEKY 270

  Fly   462 E--CLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQASDIEQTRKAVRAAIVLL 524
            |  |.|... |...||.:||..||:::|..||:.|:.||:.|||.:...:..|.|||.:|.:||:
  Fly   271 EINCPWMQE-THVDWIYQGPVCAVLIINLTFLLRIMWVLITKLRSANTVETRQYRKAAKALLVLI 334

  Fly   525 PLLGITNLLHQLAPLKTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEVRAVLLKSLAT----- 584
            ||.|||.|:....|.::.....:::.....|.|.|||.::|.|||||.|||..|...::|
  Fly   335 PLFGITYLVVLAGPSESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNSEVRNALRHHISTWRDTR 399

  Fly   585 QLSVRGHPEWAPKRASMYSGAYNTAPDTDAVQPAGDPSATGKRISPPNKRLNGRKPSSASIVMIH 649
            .:.:..:..:..|..|...|    :|..::::|.......|||.|..:      ..::.::|..|
  Fly   400 TIQLNQNRRYTTKSFSKGGG----SPRAESMRPLTSYYGRGKRESCVS------SATTTTLVGQH 454

  Fly   650 EPQQRQR-------LMPRLQNKAREKG 669
            .|....|       .||.|...|...|
  Fly   455 APLSLHRGSNNALHTMPTLAANAMSSG 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	19/58 (33%)
		7tmB1_PDFR	306..584	CDD:320389	95/287 (33%)
		TM helix 1	308..333	CDD:320389	7/24 (29%)
		TM helix 2	342..364	CDD:320389	6/21 (29%)
		TM helix 3	391..418	CDD:320389	10/26 (38%)
		TM helix 4	430..450	CDD:320389	8/24 (33%)
		TM helix 5	469..498	CDD:320389	11/28 (39%)
		TM helix 6	512..539	CDD:320389	13/26 (50%)
		TM helix 7	546..571	CDD:320389	9/24 (38%)
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	22/70 (31%)
		7tmB1_DH_R	126..394	CDD:320391	95/290 (33%)
		TM helix 1	128..153	CDD:320391	7/27 (26%)
		TM helix 2	162..184	CDD:320391	6/38 (16%)
		TM helix 3	197..224	CDD:320391	10/27 (37%)
		TM helix 4	236..256	CDD:320391	6/19 (32%)
		TM helix 5	279..308	CDD:320391	11/29 (38%)
		TM helix 6	322..349	CDD:320391	13/26 (50%)
		TM helix 7	356..381	CDD:320391	9/24 (38%)