Protein Alignment Pdfr and hec

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_572843.2
• Gene: hec / 32246
• FlyBaseID: FBgn0030437
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 498
• Identity: 138/498 - (27%)
• Similarity: 214/498 - (42%)
• Gaps: 94/498 - (18%)

  Fly   110 FESKSMLEPTSSHSLATGRVPLLHDFDASTTE--SPGTYVLDGVARVAQLALEPTVMDALPDSDT 172
            |..:::...|...|.:.|...   |:|:...|  ||....|:..      |:...|:| :.:.|.
  Fly    38 FRYQNVTYDTDDPSFSLGPAT---DYDSDLPENFSPVPRYLENA------AMNEGVID-MRNVDE 92

  Fly   173 EQVLGNLNSSAPWNLTLASAA-ATNFENCSALFVNYTLPQTGLYCNWTWDTLLCWPPTPAGVLAR 236
            |     |........|:.||. |||.:            :..|:|...:|..||||.||||.:..
  Fly    93 E-----LAEKEELMATVVSATMATNQK------------ENRLFCPLNFDGYLCWPRTPAGTVLS 140

  Fly   237 MNCPGGFHGVDTRKFAIRKCELDGRWGSRPNATEVNPPGWTDYGPCYKPEIIRLMQQMGSKDFDA 301
            ..||....|.:.:..|.:.|..:|.|...|    |:...|::|..|...|.:         :|..
  Fly   141 QYCPDFVEGFNRKFLAHKTCLENGSWYRHP----VSNQTWSNYTNCVDYEDL---------EFRQ 192

  Fly   302 YIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYLDQ 366
            :|:      .|.:.|..|||.||::|::||..|:|||..|.:||.:||.::....:..:..|
  Fly   193 FIN------ELYVKGYALSLLALLISIIIFLGFKSLRCTRIRIHVHLFASLACTCVAWILWY--- 248

  Fly   367 FRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLK 431
                  ......|.::.|| |..|...::::.|.....:.|||.|||:||.::.|...:.:..::
  Fly   249 ------RLVVERSETIAEN-PLWCIGLHLVVHYFMLVNYFWMFCEGLHLHLVLVVVFVKDTIVMR 306

  Fly   432 FFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNYNLTP--YYWILEGPRLAVILLNFCFLVNI 494
            :|..:.|..||.:..|:.  ...:..:...:..|   :|.  |.||...|....:|.:|.||:|:
  Fly   307 WFIVISWFSPIPIAIVYG--LARHFSSPDNKHCW---ITDSLYLWIFSVPITLSLLASFIFLINV 366

  Fly   495 IRVLVMKLRQSQASDIE-QTRKAVRAAIVLLPLLGITNLLHQLAPLKTATNFAVWSYGT---HF- 554
            :||:|.||....|.... ..||||||.|:|:||.|   |.|.|.|.:.       ..||   ||
  Fly   367 LRVIVRKLHPQSAQPAPLAIRKAVRATIILVPLFG---LQHFLLPYRP-------DAGTQLDHFY 421

  Fly   555 ------LTSFQGFFIALIYCFLNGEVRAV-------LLKSLAT 584
                  |.|.|||.::.::||.|.:|...       ||.||.|
  Fly   422 QMLSVVLVSLQGFVVSFLFCFANHDVTFAIRTLLNKLLPSLVT 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	19/58 (33%)
		7tmB1_PDFR	306..584	CDD:320389	89/297 (30%)
		TM helix 1	308..333	CDD:320389	10/24 (42%)
		TM helix 2	342..364	CDD:320389	4/21 (19%)
		TM helix 3	391..418	CDD:320389	9/26 (35%)
		TM helix 4	430..450	CDD:320389	5/19 (26%)
		TM helix 5	469..498	CDD:320389	11/30 (37%)
		TM helix 6	512..539	CDD:320389	14/26 (54%)
		TM helix 7	546..571	CDD:320389	11/34 (32%)
hec	NP_572843.2	HRM	118..183	CDD:397086	22/68 (32%)
		7tmB1_NPR_B4_insect-like	191..457	CDD:320388	86/296 (29%)
		TM helix 1	193..218	CDD:320388	11/30 (37%)
		TM helix 2	227..249	CDD:320388	5/30 (17%)
		TM helix 3	266..293	CDD:320388	9/26 (35%)
		TM helix 4	305..325	CDD:320388	5/21 (24%)
		TM helix 5	341..370	CDD:320388	10/28 (36%)
		TM helix 6	385..412	CDD:320388	15/36 (42%)
		TM helix 7	419..444	CDD:320388	9/24 (38%)