DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pdfr and Sctr

DIOPT Version :9

Sequence 1:	NP_001245501.1	Gene:	Pdfr / 31234	FlyBaseID:	FBgn0260753	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_001012322.2	Gene:	Sctr / 319229	MGIID:	2441720	Length:	464	Species:	Mus musculus

Alignment Length:	462	Identity:	122/462 - (26%)
Similarity:	210/462 - (45%)	Gaps:	95/462 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 SDTEQVLGNLNSSAPWNLTLASAAATNFENCSALFVNYTLPQTGLYCNWTWDTLLCWPPTPAGVL 234
            |:.::.||...:||   :..:.:|.           :||:.|.   |...||.:.|||.:.....
Mouse    51 SEEKKALGPKTASA---IVFSPSAP-----------SYTVHQG---CERFWDNMSCWPSSALAQT 98

  Fly   235 ARMNCPGGFHGVDTRKFAIRKCELDGRWGSR-PNATEVNPPGWTDYGPCYKPEIIRLMQQMGSKD 298
            ..:.||         || :|.  ..||.||. .|.|:   .||::..|  :|::...:...||
Mouse    99 VEVPCP---------KF-LRM--FSGRNGSLFRNCTK---DGWSETFP--RPDLACGVNMNGS-- 144

  Fly   299 FD----AYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIR 359
            |:    ||:   .:.:.:..||...||..|:|:|.|.|:||.|...|..||.:|||:.:|:.:..
Mouse   145 FNERRHAYL---LKLKVMYTVGYSSSLAMLLVALSILCSFRRLHCTRNYIHMHLFVSFILRALSN 206

  Fly   360 L-----------TLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMFIEGL 413
            .           ..|.|..|.|                   |:...:..:|...|.:.|:.:|||
Mouse   207 FIKDAVLFPADDVTYCDAHRAG-------------------CKLVMIFFQYCIMANYAWLLVEGL 252

  Fly   414 YLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNYNL-TPYYWILE 477
            |||.::.::.|.....|:.|...||..|.:...:|| .|..::: ..| | |:.|. ...:|::.
Mouse   253 YLHTLLAISFFSERKCLQAFVLFGWGSPAIFVALWA-VTRHFLE-DFG-C-WDINSNASIWWVIR 313

  Fly   478 GPRLAVILLNFCFLVNIIRVLVMKLR--QSQASDIEQTRKAVRAAIVLLPLLGITNLLHQLAP-- 538
            ||.:..|::||.|.:||:|:|:.|||  :::.::....::..::.::|:||.||..::...:|
Mouse   314 GPVILSIVINFIFFINILRILMRKLRTQETRGNETHHYKRLAKSTLLLIPLFGIHYIVFAFSPEG 378

  Fly   539 -LKTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEVRAVLLKSLATQLSVRGHPEWAPKRASMY 602
             ::....|.:      .|.||||..:|::||||||||:..:.|...     :.|.:..|.|....
Mouse   379 AMEVQLFFEL------ALGSFQGLVVAVLYCFLNGEVQLEVQKKWR-----QWHLQEFPLRPVAL 432

  Fly   603 SGAYNTA 609
            |.:::.|
Mouse   433 SNSFSNA 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:280888	17/59 (29%)
Pdfr	NP_001245501.1	7tm_4	306..563	CDD:304433	72/273 (26%)
Sctr	NP_001012322.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290902at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45620
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920