Protein Alignment Pdfr and mthl12

DIOPT Version :9

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_731791.2
• Gene: mthl12 / 261599
• FlyBaseID: FBgn0045442
• Length: 488
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 82/515 - (15%)
• Similarity: 176/515 - (34%)
• Gaps: 141/515 - (27%)

  Fly   104 APTAGTFESKSMLE----PTSSHSL-------------ATGRVPLLHDFDASTTESPGTYVLDGV 151
            |...|.|:.|.:::    ||...:|             ...|..:|.:.:.|          |||
  Fly    54 ANLTGEFDYKELMDGSKVPTEFPNLRGCICKVRPCIRICCARKNILSNGECS----------DGV 108

  Fly   152 ARVAQLA-LEPTVMDALPDSDTEQVLGNLNSSAPWNLTLASAAATNFENCSALFV----NYTLPQ 211
            ....:|. |:.|:.|.|.   |:..|..||....:|.|........|:.|..:..    .||:.:
  Fly   109 KNEIKLTMLDLTMQDILL---TDPTLAELNMIPQYNSTELLILREQFQPCDEIVSLKRDEYTILK 170

  Fly   212 TGLYCNWTWDTLLCWPPTPAGVLAR-MNCPGGFHGVDTRKFAIRKCELDGRWGSRPNATEVNPPG 275
            .|       ..||   .|.|.:|:. ..|                               :.|..
  Fly   171 DG-------SILL---HTSAEILSNDQYC-------------------------------LYPEI 194

  Fly   276 WTDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNN 340
            ::|:     ||.||::.:.      .|.::......|.::    |:...|::|.::.:...|||
  Fly   195 YSDF-----PETIRIINRR------CYRNVMPGIAQLSVI----SVVGFILTLAVYLSVEKLRN- 243

  Fly   341 RTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMF 405
              .:.|.|..::....:......:|.||             ::::   :|.|:..:..:...:.:
  Fly   244 --LLGKCLICSLFSMFMEYFIWTMDYFR-------------LLQS---ICSAAGYMKYFFSMSSY 290

  Fly   406 MWMFIEGLYLHNMVT-VAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLW---- 465
            :|..:...:|..:.| :...:..:....::...||...:.|.|......|: :...|:..|
  Fly   291 LWFSVVSFHLWELFTSLNRHEPQYRFLIYNTFVWCTAAIPTVVIFSMNQMW-ENDPGKSEWLPLV 354

  Fly   466 --------NYNLTPYYWILEGPRLAVILLNFCFLVNII--RVLVMKLRQSQASDIEQTRKAVRAA 520
                    ::|.:.:::    ..:.:::||...::..:  .:.:.|:::...|..:...:.....
  Fly   355 GYFGCSVKDWNSSSWFY----SHIPIVILNSFNVIMFVLTAIYIWKVKKGVKSFAQHDERNTTCL 415

  Fly   521 ----------IVLLPLLGITNLLHQLAPLKTATNFAVWSYGTHFLTSFQGFFIALIYCFL 570
                      :.|..::|.:.||.||..|...::..:.:...:........|..||:..|
  Fly   416 EFNVQTYIQFVRLFLIMGASWLLDQLTRLAEDSHLLLDTIVLNLTVYLNAAFGILIFVLL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:280888	7/59 (12%)
		7tm_4	306..563	CDD:304433	36/281 (13%)
mthl12	NP_731791.2	Methuselah_N	27..209	CDD:284145	41/219 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462249
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930