Protein Alignment Pdfr and Pth2r

DIOPT Version :9

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_644676.1
• Gene: Pth2r / 213527
• MGIID: 2180917
• Length: 546
• Species: Mus musculus
• Alignment Length: 557
• Identity: 140/557 - (25%)
• Similarity: 233/557 - (41%)
• Gaps: 117/557 - (21%)

  Fly   169 DSD-----TEQVLGNLNSSAPWNLTLASAAATNFENCSALFVNYTLPQTGLYCNWTWDTLLCWPP 228
            |||     .||::..:.:.....|.:.:.......||        .|:        ||.::|||.
Mouse    27 DSDGTITIEEQIVLVMKAKMQCELNITAQLQEGEGNC--------FPE--------WDGIICWPR 75

  Fly   229 TPAGVLARMNCPGGFHGVDTRKFAIRKCELDGRWGSRPNATEVNPPGWTDYGPCY-KPEIIRLMQ 292
            ...|.::.:.||...:..:.:..|.|.|..:|.|.|...:.:.    |.:|..|: :|:|
Mouse    76 GTVGKMSAVPCPPYVYDFNHKGVAFRHCTPNGTWDSIHGSNKT----WANYSDCFLQPDI----- 131

  Fly   293 QMGSKDF--DAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQ 355
            .:|.::|  ..||        |..||..:|..:|.|::||...||.|...|..||.:|||:.:|:
Mouse   132 NIGKQEFFESLYI--------LYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMLR 188

  Fly   356 VIIRLTLYLDQFRRGNKEAATNTSLSV--------------------IENTPYL-CEASYVLLEY 399
            .   :::::       |:......|.|                    ::.:.|: |:.:.|:..|
Mouse   189 A---MSIFV-------KDRVAQAHLGVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVMFIY 243

  Fly   400 ARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECL 464
            .....:.|:.:|||||||::.|:.|..:..|..|..:||..|.:....||.......||   .|
Mouse   244 FLATNYYWILVEGLYLHNLIFVSFFSDTKYLWGFISIGWGFPAVFVVAWAVARATLADT---RC- 304

  Fly   465 WNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQA--SDI-EQTRKAVRAAIVLLPL 526
            |..:... .||.:.|.||.|.|||...:|.:|||..|:.::.|  .|: :|.||..::.:||:.:
Mouse   305 WELSAGD-RWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDMRKQYRKLAKSTLVLVLV 368

  Fly   527 LGITNLLHQLAPLKTATNFAVWSYGTH---FLTSFQGFFIALIYCFLNGEVRAVLLKSLATQ--L 586
            .|:..::....|...:..:  |....|   |..||||||::::||:.||||:|. :|.:.|:  |
Mouse   369 FGVHYIVFVCQPHSFSGLW--WEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAE-VKKMWTRWNL 430

  Fly   587 SVRGHPEWAPKRA-----SMYSGAYNTAPDTDAVQP-----------AGDPSATGKRISPPNKRL 635
            |:    :|  |||     ..|.....|...:.:.|.           :|.|:....|....:..|
Mouse   431 SI----DW--KRAPPCGGQRYGSVLTTVTHSTSSQSQMGASTRLVLISGKPTKNACRQIDSHVTL 489

  Fly   636 NGRK-PSSASIVMIHEPQQRQRLMPRLQNKAREKGKD 671
            .|.. .||......|.|.:..:      ...|.:|.|
Mouse   490 PGYVWSSSEQDCQTHSPPEETK------EGHRRQGDD 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:280888	14/58 (24%)
		7tm_4	306..563	CDD:304433	77/283 (27%)
Pth2r	NP_644676.1	HRM	63..125	CDD:280888	18/81 (22%)
		7tm_2	139..406	CDD:278432	79/291 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..546		6/30 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290902at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45620
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920