Protein Alignment Pdfr and seb-3

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_510496.1
• Gene: seb-3 / 181598
• WormBaseID: WBGene00007664
• Length: 454
• Species: Caenorhabditis elegans
• Alignment Length: 475
• Identity: 120/475 - (25%)
• Similarity: 188/475 - (39%)
• Gaps: 117/475 - (24%)

  Fly   216 CNWTWDTLLCWPPTPAGVLARMNCP-------GGFHGVDTRKFAIRKCELDGRWGSRPNATEVNP 273
            |:..:|..|||.....|.....:||       .|...:..|....|.|...|.|..
 Worm    28 CSVDFDKSLCWASAHIGQQMTRDCPFTFCTAIPGCEEIKDRYMVSRNCNSMGVWQD--------- 83

  Fly   274 PGWTDYGPCYK----------------PEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLF 322
               ::|..|.|                |:::|          |..|.:   :.||..|    |:.
 Worm    84 ---SNYTMCIKVVEEYAQCLQGFCRVCPDVLR----------DLVISV---SLTLSFV----SVI 128

  Fly   323 ALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTP 387
            .|:.::::|..|.|::..|..|||||..|.|.:..:.....:.|        .||........||
 Worm   129 LLVAAIVLFSIFDSIQCRRLSIHKNLATAFVFRFAVLAIWTIVQ--------TTNVFQDCTRLTP 185

  Fly   388 -------YLCEASYVLLEYARTAMFMWMFIEGLYLHNMVTV-AVFQGSFPLKFFSRLGWCVPILM 444
                   ::|:|....:.|...|..|||.|||.:|::..|| |:.....|...:...||.||.::
 Worm   186 LPLWDYEWICKAILWFVIYFNVASVMWMLIEGAFLYSRFTVFAMRHSDAPWSLYLACGWGVPFVV 250

  Fly   445 TTVWARCTVMYMDTSLGECLWNYNLTPY-----YWILEGPRLAVILLNFCFLVNIIRVLVMKLRQ 504
            .|.||...............|    .||     .|||.|...:.:::|..||:.|:.:||.|||.
 Worm   251 VTAWALVHQYISSQQTNSFCW----LPYAQGLHLWILAGTMGSALIMNLIFLLMIVVILVQKLRT 311

  Fly   505 SQASDIEQTRKAVRAAIVLLPLLGITNLLHQLAPL--KTATNFAVWSYGTHFLTSFQGFFIALIY 567
            ..:::.::..:.::|.::|:|||||:|:     ||  :.....:|:..|:..|...||.|||::|
 Worm   312 ENSAESKKIWRTIKATLLLVPLLGISNI-----PLFYEPEHPSSVYMLGSAILQHSQGIFIAVLY 371

  Fly   568 CFLNGEVRAVLLKSL-----------------------ATQLSVRGHP-EWAPKRASMYSGAYNT 608
            ||||.|::..|.:.|                       |...:..|.| |...|..::.||. ||
 Worm   372 CFLNSEIQGALKRQLSKVPFEFFKTRNRFETERTYVPEARNATKNGVPMEEMNKTKNIESGE-NT 435

  Fly   609 APDTDAVQPAGDPSATGKRI 628
                    .:.|..:|||:|
 Worm   436 --------ESQDQVSTGKQI 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	14/62 (23%)
		7tmB1_PDFR	306..584	CDD:320389	85/315 (27%)
		TM helix 1	308..333	CDD:320389	6/24 (25%)
		TM helix 2	342..364	CDD:320389	7/21 (33%)
		TM helix 3	391..418	CDD:320389	10/26 (38%)
		TM helix 4	430..450	CDD:320389	6/19 (32%)
		TM helix 5	469..498	CDD:320389	10/33 (30%)
		TM helix 6	512..539	CDD:320389	8/26 (31%)
		TM helix 7	546..571	CDD:320389	11/24 (46%)
seb-3	NP_510496.1	HRM	27..90	CDD:397086	15/73 (21%)
		7tmB1_hormone_R	112..388	CDD:341321	88/309 (28%)
		TM helix 1	114..139	CDD:341321	7/31 (23%)
		TM helix 2	148..170	CDD:341321	7/21 (33%)
		TM helix 3	196..223	CDD:341321	10/26 (38%)
		TM helix 4	236..256	CDD:341321	6/19 (32%)
		TM helix 5	276..305	CDD:341321	8/28 (29%)
		TM helix 6	319..346	CDD:341321	10/31 (32%)
		TM helix 7	350..375	CDD:341321	11/24 (46%)