Protein Alignment Pdfr and CRHR2

DIOPT Version :9

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_001189404.1
• Gene: CRHR2 / 1395
• HGNCID: 2358
• Length: 438
• Species: Homo sapiens
• Alignment Length: 408
• Identity: 131/408 - (32%)
• Similarity: 196/408 - (48%)
• Gaps: 61/408 - (14%)

  Fly   215 YCNWTWDTL-LCWPPTPAGVLARMNCPGGFHGV--DTRKFAIRKCELDGRWGSRPNATEVNPPGW 276
            |||.|.|.: .|||.:.||.|....||..|:||  :|.:.|.|:|..:|.|.|:.|.::..|
Human    66 YCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEP--- 127

  Fly   277 TDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNR 341
                      |:...|    :.:|.:..||   ..:..:|.|:|:.||:.:.|:|...||:|..|
Human   128 ----------ILDDKQ----RKYDLHYRIA---LVVNYLGHCVSVAALVAAFLLFLALRSIRCLR 175

  Fly   342 TKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFM 406
            ..||.||....:|:.::...|.|             ....|.|:....|.....:..|.....|.
Human   176 NVIHWNLITTFILRNVMWFLLQL-------------VDHEVHESNEVWCRCITTIFNYFVVTNFF 227

  Fly   407 WMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNY---N 468
            |||:||.|||..:.:...........|..:|||:|..:...||...:.|.:.   :|.:..   :
Human   228 WMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENE---QCWFGKEPGD 289

  Fly   469 LTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQASDIEQTRKAVRAAIVLLPLLGITNLL 533
            |..|  |.:||.:.|:|:||.||.||:|:|:.|||.|..|:..|.||||:|.:|||||||||.:|
Human   290 LVDY--IYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYML 352

  Fly   534 HQLAPLKTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEVRAVLLK-------------SLATQ 585
            ..:.|.:...:..::.|...||.||||||:::.|||.|||||:.:.|             .:|..
Human   353 FFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARA 417

  Fly   586 LSVRGHPEWAPKRASMYS 603
            :|:    ..:|.|.|.:|
Human   418 MSI----PTSPTRISFHS 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:280888	24/59 (41%)
		7tm_4	306..563	CDD:304433	86/259 (33%)
CRHR2	NP_001189404.1	HormR	63..134	CDD:214468	27/84 (32%)
		7tm_2	140..382	CDD:278432	87/262 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2715
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840