Protein Alignment Pdfr and Crhr2

DIOPT Version :9

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_001275547.1
• Gene: Crhr2 / 12922
• MGIID: 894312
• Length: 431
• Species: Mus musculus
• Alignment Length: 419
• Identity: 137/419 - (32%)
• Similarity: 199/419 - (47%)
• Gaps: 67/419 - (15%)

  Fly   206 NYTLPQTGLYCNWTWDTL-LCWPPTPAGVLARMNCPGGFHGV--DTRKFAIRKCELDGRWGSRPN 267
            |::.|.|  |||.|.|.: .|||.:..|.|....||..|:|:  :|.:.|.|:|..:|.|.||.|
Mouse    52 NFSGPYT--YCNTTLDQIGTCWPQSAPGALVERPCPEYFNGIKYNTTRNAYRECLENGTWASRVN 114

  Fly   268 ATEVNPPGWTDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFC 332
            .:...|             |:...|    :.:|.:..||   ..:..:|.|:|:.||:.:.|:|.
Mouse   115 YSHCEP-------------ILDDKQ----RKYDLHYRIA---LIVNYLGHCVSVVALVAAFLLFL 159

  Fly   333 TFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYL--DQFRRGNKEAATNTSLSVIENTPYLCEASYV 395
            ..||:|..|..||.||....:|:.|....|.|  .:...||:               ..|.....
Mouse   160 VLRSIRCLRNVIHWNLITTFILRNIAWFLLQLIDHEVHEGNE---------------VWCRCITT 209

  Fly   396 LLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSL 460
            :..|.....|.|||:||.|||..:.:...........|..:|||:|..:...||...:.|.:.
Mouse   210 IFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIIIAWAVGKLYYENE-- 272

  Fly   461 GECLWNY---NLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQASDIEQTRKAVRAAIV 522
             :|.:..   :|..|  |.:||.:.|:|:||.||.||:|:|:.|||.|..|:..|.||||:|.:|
Mouse   273 -QCWFGKEAGDLVDY--IYQGPVMLVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLV 334

  Fly   523 LLPLLGITNLLHQLAPLKTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEVRAVLLK------- 580
            ||||||||.:|..:.|.:...:..|:.|...||.||||||:::.|||.||||||.|.|
Mouse   335 LLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYCFFNGEVRAALRKRWHRWQD 399

  Fly   581 ------SLATQLSVRGHPEWAPKRASMYS 603
                  .:|..:|:    ..:|.|.|.:|
Mouse   400 HHALRVPVARAMSI----PTSPTRISFHS 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:280888	23/61 (38%)
		7tm_4	306..563	CDD:304433	88/261 (34%)
Crhr2	NP_001275547.1	HormR	56..127	CDD:214468	28/89 (31%)
		7tm_2	133..375	CDD:278432	89/264 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2715
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840