Protein Alignment Pdfr and Adcyap1r1

DIOPT Version :9

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_006505451.1
• Gene: Adcyap1r1 / 11517
• MGIID: 108449
• Length: 523
• Species: Mus musculus
• Alignment Length: 559
• Identity: 134/559 - (23%)
• Similarity: 212/559 - (37%)
• Gaps: 188/559 - (33%)

  Fly   151 VARVAQLALEPTVMDALP-----DSD----TEQV-----------LGNLNSSAPWNLTLASAAAT 195
            :||..||:|  |.:..||     .||    .||.           |..||.|:|.
Mouse     1 MARTLQLSL--TALLLLPMAIAMHSDCIFKKEQAMCLERIQRANDLMGLNESSPG---------- 53

  Fly   196 NFENCSALFVNYTLPQTGLYCNWTWDTLLCWPPTPAGVLARMNCP-------------------G 241
                                |...||.:.||.|...|.:..::||                   .
Mouse    54 --------------------CPGMWDNITCWKPAQIGEMVLVSCPEVFRIFNPDQVWMTETIGDS 98

  Fly   242 GFHGVDTRKFAI-------RKCELDGRWGSRPNATEVNPPGWTDYGPCYKPEIIRLMQQMGSKDF 299
            ||  .|:....|       |.|..|| | |.|.....:..|:.||.|           :.|.:|:
Mouse    99 GF--ADSNSLEITDMGVVGRNCTEDG-W-SEPFPHYFDACGFDDYEP-----------ESGDQDY 148

  Fly   300 DAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYL 364
             .|:.:    :.|..||...||..|..:::|.|.||.|...|..||.||||:.:|:.|   ::::
Mouse   149 -YYLSV----KALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAI---SVFI 205

  Fly   365 DQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFP 429
            ..:....::.:::..:|.:|     |:|..|...|...:.:.|:|||||||..::....|.....
Mouse   206 KDWILYAEQDSSHCFVSTVE-----CKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRY 265

  Fly   430 LKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNYN-LTPYYWILEGPRLAVILLNFCFLVN 493
            ..:::.:||..|.:..||||...:.:.|..   | |:.| .|..:|:::||.:..|::||...:.
Mouse   266 FYWYTIIGWGTPTVCVTVWAVLRLYFDDAG---C-WDMNDSTALWWVIKGPVVGSIMVNFVLFIG 326

  Fly   494 IIRVLVMKL-------------------------------------------------------- 502
            ||.:||.||
Mouse   327 IIIILVQKLQSPDMGGNESSIYLTNLRLRVPKKAREDPLPVPSDQHSPPFLCVQKCYCKPQRAQQ 391

  Fly   503 ---RQSQASDIEQTRKAVRAAIVLLPLLGITNLLHQLAPLKTA-TNFAVWSYGTHFLTSFQGFFI 563
               :.|:.|.|  |.:..|:.::|:||.||...:...:|...: ....|:..|   |.|||||.:
Mouse   392 HSCKMSELSTI--TLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELG---LGSFQGFVV 451

  Fly   564 ALIYCFLNGEVRAVLLKSLATQLSVRGHPEWAPKRASMY 602
            |::||||||||:|.:.:            :|...:.:.|
Mouse   452 AVLYCFLNGEVQAEIKR------------KWRSWKVNRY 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:280888	20/84 (24%)
		7tm_4	306..563	CDD:304433	78/317 (25%)
Adcyap1r1	XP_006505451.1	HRM	52..137	CDD:367186	22/118 (19%)
		7tmB1_PACAP-R1	150..472	CDD:320653	90/354 (25%)
		TM helix 1	153..177	CDD:320653	7/27 (26%)
		TM helix 2	186..207	CDD:320653	8/23 (35%)
		TM helix 3	227..249	CDD:320653	7/21 (33%)
		TM helix 4	268..284	CDD:320653	4/15 (27%)
		TM helix 5	302..325	CDD:320653	7/22 (32%)
		TM helix 6	404..429	CDD:320653	6/24 (25%)
		TM helix 7	434..459	CDD:320653	12/27 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290902at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45620
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920