Protein Alignment Pdfr and glp2r

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_009304634.2
• Gene: glp2r / 101885514
• ZFINID: ZDB-GENE-050516-3
• Length: 517
• Species: Danio rerio
• Alignment Length: 513
• Identity: 145/513 - (28%)
• Similarity: 222/513 - (43%)
• Gaps: 115/513 - (22%)

  Fly   172 TEQVLGNLNSSAPWNL-----TLASAAATN---------FENCSALFVNYTLPQ-TGLYCNWTWD 221
            ||..:|...||||..|     |..|.:..:         .|||:. |:..|||. ||.:||.|:|
Zfish     3 TELQMGRRRSSAPLLLLFLCCTPVSGSVLDDLIYKRSEYQENCTR-FLTATLPAGTGTFCNGTFD 66

  Fly   222 TLLCWPPTPAGVLARMNCP--------GGFHGVDTRKFAIRKCELDGRWGSRPNATEVNPPGWTD 278
            ...|||.:..||:: :.||        |....|      .::|.::|.|.:..|::.|    |.:
Zfish    67 VFACWPHSSPGVVS-VPCPPYLPWIREGATGNV------YKECTVNGTWKTEENSSSV----WRN 120

  Fly   279 YGPCYKPEIIRLMQQMGSKDFDAYIDIARRT--RTLEIVGLCLSLFALIVSLLIFCTFRSLRNNR 341
            ...|......:..::          ::.|::  |.|.|||..||..:|.:::||....|.|...|
Zfish   121 QSECENHYFFKSEEE----------EVFRQSVLRVLSIVGYSLSFSSLCLAVLIMSLLRKLHCTR 175

  Fly   342 TKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTP---------------YLCE 391
            ..||.||||:.:.:.|..:|          ||.....:.|   |.|               ::|:
Zfish   176 NYIHINLFVSFMFRAIAVIT----------KEVILQVAYS---NLPRDEVGWNSYTKSAISFICK 227

  Fly   392 ASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYM 456
            ||.|.|||.....:.|:.:|.::||.::..||......||.:..:||..|:|....|.....:|.
Zfish   228 ASKVSLEYFVGCNYFWLLVEAVFLHTLLFTAVLTRKTLLKKYIFIGWGTPLLFVIPWTVAKTLYE 292

  Fly   457 DTSLGECLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQASDIEQTRKAVRAAI 521
            :.|   | |..|:...:||:.||....:::.||..:.|||:|:.||:..|....:......||.:
Zfish   293 NKS---C-WMNNIRWIWWIIRGPITLSVIVIFCIFLKIIRLLLSKLKADQVKFTDYRYSLARATL 353

  Fly   522 VLLPLLGITNLLHQL-------APLKTATNFAVWSYGTHF-LTSFQGFFIALIYCFLNGEVRAVL 578
            ||:||||:..::..|       ...:.|.||      .|. |:||||..:|::|||.||||:|.|
Zfish   354 VLIPLLGVHEIVFTLIIDESVEGSNRYARNF------VHLTLSSFQGLIVAVLYCFANGEVQAEL 412

  Fly   579 LKSLATQLSVRG------------HPE--W-----APKRASMYSGAYNTAPDTDAVQP 617
            .|  ..||.|..            ||:  |     :|:....::.. |...|.|..||
Zfish   413 KK--RWQLLVSSSSFEVHSCFSDIHPKHLWKFSQKSPRPHPQHTDT-NEEGDQDTSQP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	18/66 (27%)
		7tmB1_PDFR	306..584	CDD:320389	94/302 (31%)
		TM helix 1	308..333	CDD:320389	10/26 (38%)
		TM helix 2	342..364	CDD:320389	8/21 (38%)
		TM helix 3	391..418	CDD:320389	10/26 (38%)
		TM helix 4	430..450	CDD:320389	7/19 (37%)
		TM helix 5	469..498	CDD:320389	9/28 (32%)
		TM helix 6	512..539	CDD:320389	9/33 (27%)
		TM helix 7	546..571	CDD:320389	10/25 (40%)
glp2r	XP_009304634.2	None