Protein Alignment Pdfr and vipr1

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_031759879.1
• Gene: vipr1 / 100497291
• XenbaseID: XB-GENE-5991267
• Length: 444
• Species: Xenopus tropicalis
• Alignment Length: 385
• Identity: 110/385 - (28%)
• Similarity: 171/385 - (44%)
• Gaps: 58/385 - (15%)

  Fly   206 NYTLPQTGLYCNWTWDTLLCWPPTPAGVLARMNCP---GGFHGVDTRKFAIRKCELDGRWGSRPN 267
            |:||.     |..:||.:.||.....|.:..|.||   |.|..|....             || |
 Frog    48 NHTLG-----CKASWDNITCWRSASVGEVVVMPCPDYFGFFSNVQGNV-------------SR-N 93

  Fly   268 ATEVNPPGWTDYGPCYKPEIIRL-----MQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVS 327
            .||   .||||..|.  |..|..     ....|..:|.:.|      :|...:|..:||.:|..:
 Frog    94 CTE---HGWTDMFPA--PYAIACGFDTNNTTNGQTEFFSMI------KTGYTIGHSVSLISLTAA 147

  Fly   328 LLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEA 392
            ::|...||.|...|..||.:||::.:::.|......:..|..|..:.....|:.        |:|
 Frog   148 MIILFFFRKLHCTRNYIHMHLFMSFIMRAIAVFVKDIVLFESGEFDHCFVGSVG--------CKA 204

  Fly   393 SYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMD 457
            :.|..:|...|.|.|:.:||||||.::.::.|.......::..:||..|.:..|.|....:.:.|
 Frog   205 AMVFFQYCIMANFFWLLVEGLYLHTLLVISFFSEKKYFWWYILIGWGSPTVFITAWTVTRIHFDD 269

  Fly   458 TSLGECLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQA--SDIEQTRKAVRAA 520
            :.   | |:...:|::||:..|.|..|.:||.|.:.|||:||.||.....  ::..|..:..::.
 Frog   270 SG---C-WDTIESPFWWIIRAPILISISVNFIFFICIIRILVQKLHSPDVGRNENSQYTRLAKST 330

  Fly   521 IVLLPLLGITNLLHQLAP--LKTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEVRAVL 578
            ::|:||.|:..::....|  .|......|    ...|.|||||.:|::||||||||:..|
 Frog   331 LLLIPLFGVHYIMFAFFPDNFKVEIKLIV----ELVLGSFQGFVVAILYCFLNGEVQGEL 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	17/61 (28%)
		7tmB1_PDFR	306..584	CDD:320389	80/277 (29%)
		TM helix 1	308..333	CDD:320389	6/24 (25%)
		TM helix 2	342..364	CDD:320389	5/21 (24%)
		TM helix 3	391..418	CDD:320389	12/26 (46%)
		TM helix 4	430..450	CDD:320389	5/19 (26%)
		TM helix 5	469..498	CDD:320389	12/28 (43%)
		TM helix 6	512..539	CDD:320389	6/28 (21%)
		TM helix 7	546..571	CDD:320389	11/24 (46%)
vipr1	XP_031759879.1	HormR	50..120	CDD:214468	26/93 (28%)
		7tm_GPCRs	126..392	CDD:475119	81/283 (29%)
		TM helix 1	129..153	CDD:320397	7/29 (24%)
		TM helix 2	162..183	CDD:320397	5/20 (25%)
		TM helix 3	203..225	CDD:320397	7/21 (33%)
		TM helix 4	244..260	CDD:320397	4/15 (27%)
		TM helix 5	277..300	CDD:320397	9/22 (41%)
		TM helix 6	327..349	CDD:320397	4/21 (19%)
		TM helix 7	354..379	CDD:320397	11/28 (39%)