DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdfr and vipr1

DIOPT Version :9

Sequence 1:	NP_001245501.1	Gene:	Pdfr / 31234	FlyBaseID:	FBgn0260753	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	XP_031759879.1	Gene:	vipr1 / 100497291	XenbaseID:	XB-GENE-5991267	Length:	444	Species:	Xenopus tropicalis

Alignment Length:	385	Identity:	110/385 - (28%)
Similarity:	171/385 - (44%)	Gaps:	58/385 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 NYTLPQTGLYCNWTWDTLLCWPPTPAGVLARMNCP---GGFHGVDTRKFAIRKCELDGRWGSRPN 267
            |:||.     |..:||.:.||.....|.:..|.||   |.|..|....             || |
Frog    48 NHTLG-----CKASWDNITCWRSASVGEVVVMPCPDYFGFFSNVQGNV-------------SR-N 93

  Fly   268 ATEVNPPGWTDYGPCYKPEIIRL-----MQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVS 327
            .||   .||||..|.  |..|..     ....|..:|.:.|      :|...:|..:||.:|..:
Frog    94 CTE---HGWTDMFPA--PYAIACGFDTNNTTNGQTEFFSMI------KTGYTIGHSVSLISLTAA 147

  Fly   328 LLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEA 392
            ::|...||.|...|..||.:||::.:::.|......:..|..|..:.....|:.        |:|
Frog   148 MIILFFFRKLHCTRNYIHMHLFMSFIMRAIAVFVKDIVLFESGEFDHCFVGSVG--------CKA 204

  Fly   393 SYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMD 457
            :.|..:|...|.|.|:.:||||||.::.::.|.......::..:||..|.:..|.|....:.:.|
Frog   205 AMVFFQYCIMANFFWLLVEGLYLHTLLVISFFSEKKYFWWYILIGWGSPTVFITAWTVTRIHFDD 269

  Fly   458 TSLGECLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQA--SDIEQTRKAVRAA 520
            :.   | |:...:|::||:..|.|..|.:||.|.:.|||:||.||.....  ::..|..:..::.
Frog   270 SG---C-WDTIESPFWWIIRAPILISISVNFIFFICIIRILVQKLHSPDVGRNENSQYTRLAKST 330

  Fly   521 IVLLPLLGITNLLHQLAP--LKTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEVRAVL 578
            ::|:||.|:..::....|  .|......|    ...|.|||||.:|::||||||||:..|
Frog   331 LLLIPLFGVHYIMFAFFPDNFKVEIKLIV----ELVLGSFQGFVVAILYCFLNGEVQGEL 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:280888	17/61 (28%)
Pdfr	NP_001245501.1	7tm_4	306..563	CDD:304433	70/260 (27%)
vipr1	XP_031759879.1	HormR	50..120	CDD:214468	26/93 (28%)
		7tm_GPCRs	126..392	CDD:421689	81/283 (29%)
		TM helix 1	128..153	CDD:410628	7/30 (23%)
		TM helix 2	162..184	CDD:410628	5/21 (24%)
		TM helix 3	203..230	CDD:410628	12/26 (46%)
		TM helix 4	242..262	CDD:410628	5/19 (26%)
		TM helix 5	277..306	CDD:410628	12/28 (43%)
		TM helix 6	322..349	CDD:410628	5/26 (19%)
		TM helix 7	354..379	CDD:410628	11/28 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290902at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45620
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110