DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pdfr and gipr

DIOPT Version :9

Sequence 1:	NP_001245501.1	Gene:	Pdfr / 31234	FlyBaseID:	FBgn0260753	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	XP_002932679.2	Gene:	gipr / 100490534	XenbaseID:	XB-GENE-982062	Length:	450	Species:	Xenopus tropicalis

Alignment Length:	433	Identity:	134/433 - (30%)
Similarity:	202/433 - (46%)	Gaps:	51/433 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 PQTGLYCNWTWDTLLCWPPTPAGVLARMNCPG--GFHGVDTRKFAIRKCELDGRW-GSRPNATEV 271
            |.:|::||.|:|...||..|||.......||.  .:|......|..|:|:.||:| ....|:|
Frog    44 PLSGVFCNRTFDYYACWGDTPANTTTGEPCPFYLPWHAKVKEGFVFRRCDADGQWVRDDSNST-- 106

  Fly   272 NPPGWTDYGPC--YKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTF 334
                |.|:..|  ::||      |...:.:     |..:.|.:..||..:||.||||::.|....
Frog   107 ----WRDHSQCETHEPE------QSPHEPW-----ILSKLRVMYSVGYGISLAALIVAVFILTQL 156

  Fly   335 RSLRNNRTKIHKNLFVAMVLQVIIRLT----LYLDQFRRGNKEAATNTSLSVIENTPYL-CEASY 394
            |.||..|..||.||||:.:|:.:..||    |.|..    |.........:::.|...: |..:.
Frog   157 RRLRCTRNLIHCNLFVSFILRGVSLLTRDALLPLHH----NMIQGEGDPTNLLRNRTLVGCRVAQ 217

  Fly   395 VLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTS 459
            .:.:|...|.:.|:.:|||||||::.|..|.....|..:..|||..|:|....|.....:|.::.
Frog   218 SITQYCVAANYYWLLVEGLYLHNLLVVLSFSEESVLPRYMLLGWGAPVLFVVPWVVVRQLYENSV 282

  Fly   460 LGECLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQASDIEQTRKAVRAAIVLL 524
            ..|...||:   ::||:..|.|..:|:||...:.|||:||:|||.:|....::..:..::.:.|:
Frog   283 CWERNDNYS---HWWIIRSPILLAVLINFFIFLRIIRILVLKLRANQMRRSDRKYRLAKSTLTLI 344

  Fly   525 PLLGITNLLHQLAPLKTATNFAVWSYG----THFLTSFQGFFIALIYCFLNGEVRAVLLKSLATQ 585
            |||||...:..|.|.::|....  .||    ...|:||||..:|::||..|.||:|.|.:.|...
Frog   345 PLLGIHEAVFNLLPEESARGGV--RYGKLGAELLLSSFQGLLVAVLYCLCNKEVQAELRRKLQGS 407

  Fly   586 LSVRG-----HPEWAPKRASMYSGAYNTAPDTDAVQPAGDPSA 623
            ||.||     .|...|:      |...||.|..:......|||
Frog   408 LSSRGLFSAARPLRPPQ------GRPRTAEDLMSDSSEATPSA 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:280888	21/61 (34%)
Pdfr	NP_001245501.1	7tm_4	306..563	CDD:304433	83/265 (31%)
gipr	XP_002932679.2	HRM	47..116	CDD:397086	24/74 (32%)
		7tmB1_GlucagonR-like	128..406	CDD:341353	92/286 (32%)
		TM helix 1	131..155	CDD:341353	10/23 (43%)
		TM helix 2	164..185	CDD:341353	9/20 (45%)
		TM helix 3	214..236	CDD:341353	4/21 (19%)
		TM helix 4	255..271	CDD:341353	5/15 (33%)
		TM helix 5	289..312	CDD:341353	9/25 (36%)
		TM helix 6	337..359	CDD:341353	7/21 (33%)
		TM helix 7	368..393	CDD:341353	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290902at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010