Protein Alignment Pdfr and vipr1a

DIOPT Version :10

• Sequence 1: NP_001245501.1
• Gene: Pdfr / 31234
• FlyBaseID: FBgn0260753
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_002660843.2
• Gene: vipr1a / 100334247
• ZFINID: ZDB-GENE-070912-506
• Length: 440
• Species: Danio rerio
• Alignment Length: 450
• Identity: 125/450 - (27%)
• Similarity: 198/450 - (44%)
• Gaps: 94/450 - (20%)

  Fly   216 CNWTWDTLLCWPPTPAGVLARMNCPGGFHGVDTRKFAIRK-CELDGRWGSRPNATEVNPPGWTDY 279
            |...|| |.|||....|.:..:.||..|..|..:...|.| |..|| |      ||:|.. ...|
Zfish    49 CTGEWD-LACWPSARIGEVVTIPCPNYFSHVSDQIGNISKSCTADG-W------TEINSV-VVAY 104

  Fly   280 GPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKI 344
            ...|.|.|.. ...||        :.....||...:|..:||.:||::::|.|.||.|...|..|
Zfish   105 NCGYDPNITE-DGNMG--------EFLSSVRTGYTIGHTVSLISLIIAIIILCFFRKLHCTRNYI 160

  Fly   345 HKNLFVAMVLQ---VIIR-LTLY----LDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYAR 401
            |.:||::.:|:   ||:: :.||    .|....|:..                |:|:.|..:|..
Zfish   161 HIHLFMSFILKAVAVIMKDVVLYEVEEPDDCHYGSVG----------------CKAAMVFFQYGV 209

  Fly   402 TAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWN 466
            .|.|.|:.:||||||.::.|:.|.......::..:||.||.:..|:|: .|..|:. .:| | |:
Zfish   210 MASFFWLLVEGLYLHALLAVSFFSERKYFWWYILIGWGVPGVFITIWS-ITKAYLH-DIG-C-WD 270

  Fly   467 YNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKL--RQSQASDIEQTRKAVRAAIVLLPLLGI 529
            :.....:||::.|.|..||:||...:.|||:|..|:  |....::..|..:..::.::|:||.||
Zfish   271 FIDDDLWWIIKTPTLITILMNFILFICIIRILRQKISCRDIGRNESHQYSRLAKSTLLLIPLFGI 335

  Fly   530 TNLLHQLAPLKTATNFAVWSYGTH------------FLTSFQGFFIALIYCFLNGEVRAVLLKSL 582
                          |:.::::..|            .|.|||||.:|::||||||||::.:.:
Zfish   336 --------------NYIIFAFMPHHIQSYIRLVFDLILGSFQGFCVAVLYCFLNGEVQSEIKR-- 384

  Fly   583 ATQLSVRGHPEWAPKRASMYSGAYNTAPDTDAVQPAGDPSATGKRISPPNKRLNGRKPSS 642
                      :|.......:.||     ||...||:  .::.|...|.....:....||:
Zfish   385 ----------KWRRWHMQRFLGA-----DTKYHQPS--TASNGLNFSSQITMMTKCSPST 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdfr	NP_001245501.1	HRM	213..272	CDD:397086	20/56 (36%)
		7tmB1_PDFR	306..584	CDD:320389	87/299 (29%)
		TM helix 1	308..333	CDD:320389	8/24 (33%)
		TM helix 2	342..364	CDD:320389	9/29 (31%)
		TM helix 3	391..418	CDD:320389	12/26 (46%)
		TM helix 4	430..450	CDD:320389	6/19 (32%)
		TM helix 5	469..498	CDD:320389	11/28 (39%)
		TM helix 6	512..539	CDD:320389	6/26 (23%)
		TM helix 7	546..571	CDD:320389	11/36 (31%)
vipr1a	XP_002660843.2	HRM	46..>96	CDD:397086	18/54 (33%)
		7tm_GPCRs	124..388	CDD:475119	88/309 (28%)
		TM helix 1	125..149	CDD:410628	8/23 (35%)
		TM helix 2	158..179	CDD:410628	7/20 (35%)
		TM helix 3	199..221	CDD:410628	7/21 (33%)
		TM helix 4	240..256	CDD:410628	5/15 (33%)
		TM helix 5	273..296	CDD:410628	8/22 (36%)
		TM helix 6	323..345	CDD:410628	6/35 (17%)
		TM helix 7	350..375	CDD:410628	10/24 (42%)