DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment boi and Mypn

DIOPT Version :9

Sequence 1:	NP_001096868.3	Gene:	boi / 31229	FlyBaseID:	FBgn0040388	Length:	1105	Species:	Drosophila melanogaster
Sequence 2:	NP_001355746.1	Gene:	Mypn / 309760	RGDID:	1308510	Length:	1306	Species:	Rattus norvegicus

Alignment Length:	511	Identity:	108/511 - (21%)
Similarity:	172/511 - (33%)	Gaps:	173/511 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 SEPYLYLRPSAGYNVTSGSDGLAWRLRIYVSAQTAGDYQCVAWYGPGALASTP----ARLALVSI 136
            :||.:   |:..|::|||:.                       :.|..::.||    .|:
  Rat   776 AEPAV---PTVSYSITSGNQ-----------------------FQPHCVSPTPVSPTGRI----- 809

  Fly   137 ALDVGQGSMGARSSI---RWSVAPKNCLLIRCGSVISNPPAIWSFYRNGKKLPQS---ELLPGAA 195
                 |..:...||:   ..|:.|.|.:.:. .|..|.||.  ...:...|.||:   :.:....
  Rat   810 -----QNPVAFLSSVLPSLPSIPPTNAMGLP-KSAPSVPPQ--GLMKKTTKTPQAVSDDYIRETK 866

  Fly   196 GALVLDTVTAKDAGNYSCVATN----SITGDELRLPQTIELRVDYT-----------DRTP---- 241
            .:::||  ..|.. |:|.|.::    .|:..|.||...||.|::.|           |..|
  Rat   867 NSVILD--LGKKV-NFSDVRSHQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIQHDEIPTGKC 928

  Fly   242 --PYFLQRPPIEYSARPGETVVLECPGVGSPRPRVIW-SSPNVVEIYNNRSTILSYG-----LQI 298
              |.|.:|.. .:....|..|...|..||.|.|:|.| .....:...|....:...|     |.|
  Rat   929 IAPIFDKRLK-HFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRRDGDGTCSLHI 992

  Fly   299 TDVKPEDQGSYICM--------------------LDNGIAPPIDHTIKLSVLQ------------ 331
            .....:|.|:|..|                    :.|.::|........|.:|
  Rat   993 ESTHGDDDGNYTIMAANPQGRISCSGHLMVQGFPIRNRLSPAGQSHRGRSRMQERDKEPLQERFF 1057

  Fly   332 RPTILRGPAATLTNESNPLLLDCSASGNPQPDIYWLINGEDATKDPEAVVDNR-----SLQLKRV 391
            ||..|:.|...:.:|.....|||..||.|.|::.||:||:....|....:..|     ||.:..:
  Rat  1058 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPL 1122

  Fly   392 QKRHAGVVQCFAKNILGETS----------------------------EGNILRVN--------P 420
            .:|.||...|.|.|..|:.|                            ||:.:|:.        |
  Rat  1123 TQRDAGTYTCVATNKTGQNSFSLELTVVAKEVKKAPVILEKLQNSGVPEGHPVRLEGRVIGMPPP 1187

  Fly   421 LEITGEDDEPL--------------GEV--PVWPVHESNTGMGTSSTSGGSKNKSG 460
            :....:|:|.:              |.|  .:.|..:|:.|..|.|    :||::|
  Rat  1188 VFYWKKDNETIPFTRERISMHQDTTGYVCLLIQPAKKSDAGWYTLS----AKNEAG 1239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
boi	NP_001096868.3	IG_like	42..131	CDD:214653	10/58 (17%)
		IG_like	154..234	CDD:214653	22/86 (26%)
		Ig	172..234	CDD:299845	17/68 (25%)
		IG_like	249..329	CDD:214653	19/105 (18%)
		Ig	257..329	CDD:299845	19/97 (20%)
		IG_like	339..418	CDD:214653	27/111 (24%)
		Ig	352..408	CDD:299845	21/60 (35%)
		FN3	470..592	CDD:238020
		FN3	613..700	CDD:238020
Mypn	NP_001355746.1	I-set	262..348	CDD:336764
		I-set	422..519	CDD:336764
		I-set	931..1022	CDD:336764	20/91 (22%)
		I-set	1059..1149	CDD:336764	27/89 (30%)
		Ig	1175..1249	CDD:353325	14/69 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44170
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100