DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tko and Mrps12

DIOPT Version :9

Sequence 1:	NP_001245490.1	Gene:	tko / 31228	FlyBaseID:	FBgn0003714	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	NP_001099709.1	Gene:	Mrps12 / 292758	RGDID:	1306221	Length:	139	Species:	Rattus norvegicus

Alignment Length:	115	Identity:	73/115 - (63%)
Similarity:	84/115 - (73%)	Gaps:	4/115 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 AVRGMASLQQMHRSGPHIKTRPPRQ--PLDGKPFAKGVVLKTLIKKPKKPNSANRKCVLVRLSTG 102
            |.|.||:|.||||.|.  ...||::  |.:|:|..|||||:|.|:||||||||||||..||||||
  Rat    26 ATRSMATLNQMHRLGR--PKEPPKRLGPTEGRPQLKGVVLRTFIRKPKKPNSANRKCCRVRLSTG 88

  Fly   103 KEMVAYIPGIGHNLQEHNIVLCRVGRLQDVPGVKLKAVRGVYDLAHVVKK 152
            ||.|.:|||.||.||||::||...||.||:||||||.|||.||..||.||
  Rat    89 KEAVCFIPGEGHTLQEHHVVLVEGGRTQDLPGVKLKVVRGKYDCGHVQKK 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tko	NP_001245490.1	Ribosomal_S12	46..152	CDD:239466	67/107 (63%)
Mrps12	NP_001099709.1	Ribosomal_S12	32..138	CDD:239466	67/107 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346228
Domainoid	1	1.000	121	1.000	Domainoid score	I5576
eggNOG	1	0.900	-	-		E1_COG0048
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6848
Inparanoid	1	1.050	143	1.000	Inparanoid score	I4375
OMA	1	1.010	-	-		QHG49546
OrthoDB	1	1.010	-	-		D1542634at2759
OrthoFinder	1	1.000	-	-		FOG0003097
OrthoInspector	1	1.000	-	-		oto95920
orthoMCL	1	0.900	-	-		OOG6_101451
Panther	1	1.100	-	-	LDO	PTHR11652
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2071
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770