Protein Alignment gt and TEF

DIOPT Version :9

• Sequence 1: NP_525049.1
• Gene: gt / 31227
• FlyBaseID: FBgn0001150
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_003207.1
• Gene: TEF / 7008
• HGNCID: 11722
• Length: 303
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 78/369 - (21%)
• Similarity: 129/369 - (34%)
• Gaps: 138/369 - (37%)

  Fly   111 PRKTPSPYQTSYSYGSGSPSASPTSNLLYAAQMQQQQHQQQQQQQQQQQQL-------------- 161
            |:..|.|   .....:|....|.:..|:....|:....:.:..:::.:::|
Human    14 PQAGPGP---GPGRAAGERGLSGSFPLVLKKLMENPPREARLDKEKGKEKLEEDEAAAASTMAVS 75

  Fly   162 ASLYPAFYYSNIKQE--------------------QATPT-AAPPKVTPTANLLQTFAAASAAAA 205
            |||.|..:...|..:                    .|:|| .|...:.|.|.|          ..
Human    76 ASLMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLLLPVAEL----------EG 130

  Fly   206 AAAAASSTNSPRPASNASTMQ----IDVLENPLSPAVEATTPTTSSSGEAGKNTRPFKAFPRDPL 266
            ..:|:|||.|| |:|:.:..|    :...|:.|....|..:|...:..|...|..|      ||
Human   131 KESASSSTASP-PSSSTAIFQPSETVSSTESSLEKERETPSPIDPNCVEVDVNFNP------DP- 187

  Fly   267 VIAANFAATDV---LLDNPRVERYTEYRKRVLEQIRSSNGGSRTVTNPKMRRTNSRSGSVNEGSS 328
               |:...:.|   .|.|||..::.|      |.::         ..|.:::
Human   188 ---ADLVLSSVPGGELFNPRKHKFAE------EDLK---------PQPMIKK------------- 221

  Fly   329 SNNNSESEDRAAAEESSDCDSQAGNFESKSATSSSSNLANATAANSGISSGSQVKDAAYYERRRK 393
                        |::....|.|                                ||..|:.||:|
Human   222 ------------AKKVFVPDEQ--------------------------------KDEKYWTRRKK 242

  Fly   394 NNAAAKKSRDRRRIKEDEIAIRAAYLERQNIELLCQIDALKVQL 437
            ||.|||:|||.||:||::|.||||:||::|..|..::..|:.::
Human   243 NNVAAKRSRDARRLKENQITIRAAFLEKENTALRTEVAELRKEV 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gt	NP_525049.1	bZIP_HLF	383..440	CDD:269843	28/55 (51%)
		coiled coil	384..440	CDD:269843	27/54 (50%)
TEF	NP_003207.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63		8/51 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..176		13/44 (30%)
		bZIP_HLF	232..290	CDD:269843	28/55 (51%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	235..255		12/19 (63%)
		coiled coil	236..287	CDD:269843	26/51 (51%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	256..263		3/6 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4910
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11988
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.860