DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gt and Hlf

DIOPT Version :9

Sequence 1:	NP_525049.1	Gene:	gt / 31227	FlyBaseID:	FBgn0001150	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	XP_006247198.1	Gene:	Hlf / 690286	RGDID:	1582828	Length:	296	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	74/365 - (20%)
Similarity:	126/365 - (34%)	Gaps:	146/365 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 VETPRKTPSPYQTSYSY----------GSGSPSA------SPT---SNLLYAAQMQQQQHQQQQQ 153
            :|.|.|.|...:.::|.          ||.||:.      .||   ..|.|.....|.::...::
  Rat    26 LENPLKLPLHPEDAFSKDRDKGKKLDDGSNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEE 90

  Fly   154 QQQQQQQLASLYPAFYYSNIKQEQATPTAAPPKVTPTANLLQTFAAASAAAAAAAAASSTNSPR- 217
            ...:.    .:.|:       ..|...:..||.:.|         |:|.|.:....:|...:|.
  Rat    91 FLSEN----GIPPS-------PSQHDHSPHPPGLQP---------ASSTAPSVMDLSSRATAPLH 135

  Fly   218 ---PASNASTMQIDVLENPLSPAVEATTPTTSSSGE---AGKNT-RPFK--------AFPRDPLV 267
               |:.|.       ::||:.|            |:   |.:|| .|..        .:..||..
  Rat   136 PGIPSPNC-------MQNPIRP------------GQLLPANRNTPSPIDPDTIQVPVGYEPDPAD 181

  Fly   268 IAANFAATDVLLDNPRVERYTEYRKRVLEQIRSSNGGSRTVTNPKMRRTNSRSGSVNEGSSSNNN 332
            :|.:......:.| ||..:::|...:....|:.    :|.|..|                   ::
  Rat   182 LALSSIPGQEMFD-PRKRKFSEEELKPQPMIKK----ARKVFIP-------------------DD 222

  Fly   333 SESEDRAAAEESSDCDSQAGNFESKSATSSSSNLANATAANSGISSGSQVKDAAYYERRRKNNAA 397
            .:.:|:                                                |:.||||||.|
  Rat   223 LKQDDK------------------------------------------------YWARRRKNNMA 239

  Fly   398 AKKSRDRRRIKEDEIAIRAAYLERQNIELLCQIDALKVQL 437
            ||:|||.||:||::|||||::||::|..|..::..|:.:|
  Rat   240 AKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKEL 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gt	NP_525049.1	bZIP_HLF	383..440	CDD:269843	28/55 (51%)
gt	NP_525049.1	coiled coil	384..440	CDD:269843	28/54 (52%)
Hlf	XP_006247198.1	bZIP_HLF	226..284	CDD:269843	29/102 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11988
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010