Protein Alignment gt and CEBPE

DIOPT Version :10

• Sequence 1: NP_525049.1
• Gene: gt / 31227
• FlyBaseID: FBgn0001150
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_001796.2
• Gene: CEBPE / 1053
• HGNCID: 1836
• Length: 281
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 56/239 - (23%)
• Similarity: 85/239 - (35%)
• Gaps: 62/239 - (25%)

  Fly   231 ENPLSPAVEATTPTTSSSGEAGKNTRPFKAFPRDPLVIAANFAATDVLLDNPRVERYTEY----- 290
            |..|...:.|..|...:.|..|..|   .|||.             .|..:||...|..:
Human    50 EEQLLSDLFAVKPAPEARGLKGPGT---PAFPH-------------YLPPDPRPFAYPPHTFGPD 98

  Fly   291 RKRVLEQIRSSNGGSRTVTNPKMRRTNSRSGSVNEGSSSNNNSESEDRAAAE----ESSDCDSQA 351
            ||.:...|.||.|.           .:.|:.:|.|.......|.:..|.:..    :.:.|...|
Human    99 RKALGPGIYSSPGS-----------YDPRAVAVKEEPRGPEGSRAASRGSYNPLQYQVAHCGQTA 152

  Fly   352 GN--------------FESKSATSS--SSNLANATAANSGISSGSQV--KDAAYYE-RRRKNNAA 397
            .:              .::..||::  .|.|..|.:....:..|.:.  ||:..|. ||.:||.|
Human   153 MHLPPTLAAPGQPLRVLKAPLATAAPPCSPLLKAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIA 217

  Fly   398 AKKSRD--RRRIKEDEIAIRAAYLE----RQNIELLCQ-IDALK 434
            .:||||  :|||.|.:..:.....|    |..:|.|.| :|.|:
Human   218 VRKSRDKAKRRILETQQKVLEYMAENERLRSRVEQLTQELDTLR 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gt	NP_525049.1	bZIP_HLF	383..440	CDD:269843	23/60 (38%)
		coiled coil	384..440	CDD:269843	22/59 (37%)
CEBPE	NP_001796.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		PHA03247	<62..192	CDD:223021	29/156 (19%)
		bZIP_CEBPE	202..262	CDD:269863	23/60 (38%)
		coiled coil	204..262	CDD:269863	21/58 (36%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	208..228		9/19 (47%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	230..237		1/6 (17%)