DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gt and CEBPD

DIOPT Version :9

Sequence 1:	NP_525049.1	Gene:	gt / 31227	FlyBaseID:	FBgn0001150	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_005186.2	Gene:	CEBPD / 1052	HGNCID:	1835	Length:	269	Species:	Homo sapiens

Alignment Length:	100	Identity:	27/100 - (27%)
Similarity:	44/100 - (44%)	Gaps:	4/100 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   339 AAAEESSDCDSQAGNFESKSATSSSSNLANATAANSGISSGSQVKDAAYYERRRKNNAAAKKSRD 403
            |||.:.:...|......|...|.:.......:|...|...||    ..|.:||.:||.|.:||||
Human   150 AAAGQPTPPTSPEPPRSSPRQTPAPGPAREKSAGKRGPDRGS----PEYRQRRERNNIAVRKSRD 210

  Fly   404 RRRIKEDEIAIRAAYLERQNIELLCQIDALKVQLA 438
            :.:.:..|:..:...|..:|.:|..:::.|...||
Human   211 KAKRRNQEMQQKLVELSAENEKLHQRVEQLTRDLA 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gt	NP_525049.1	bZIP_HLF	383..440	CDD:269843	16/55 (29%)
gt	NP_525049.1	coiled coil	384..440	CDD:269843	16/54 (30%)
CEBPD	NP_005186.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..48
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	97..133
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	151..219		19/71 (27%)
		bZIP_CEBPD	188..252	CDD:269862	18/61 (30%)
		coiled coil	191..249	CDD:269862	17/58 (29%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	195..222		10/26 (38%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	226..254		5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810