Protein Alignment PsGEF and CG5921

DIOPT Version :9

• Sequence 1: NP_996333.4
• Gene: PsGEF / 31224
• FlyBaseID: FBgn0264598
• Length: 2777
• Species: Drosophila melanogaster
• Sequence 2: NP_727061.2
• Gene: CG5921 / 31538
• FlyBaseID: FBgn0029835
• Length: 886
• Species: Drosophila melanogaster
• Alignment Length: 1112
• Identity: 217/1112 - (19%)
• Similarity: 342/1112 - (30%)
• Gaps: 365/1112 - (32%)

  Fly  1170 LVNAALGSTPLSSPLD-------SPDVLNTLVPLSDIGLTTASMGSMKLPSLDSIH-LKQQQKQQ 1226
            |.|:|  ||..||.:.       |.||: ||.       |||:.....:|:...:. |:..:..|
  Fly    17 LTNSA--STDCSSSMQGSTTSSASSDVM-TLT-------TTAASSWCAIPASSRLRVLRLVRPHQ 71

  Fly  1227 RTNNSHGHVHSATGVATDRTADRSHGH----NHGIHGGHVEQIELLIDEKCRILNKTGTPKSSAL 1287
            |.....|....:|...|.| ..|.||.    :|..|||......|.|.:  :||...|.....|:
  Fly    72 RRLLVGGPERGSTYGFTVR-GGREHGTGFFVSHVEHGGEAHLKGLRIGD--QILRINGFRLDDAV 133

  Fly  1288 HLANWMKGQLDKQQQQARLAAIARSQENVSAEDEQLIFNSDSEQDERITYWTRQQLEKRTKELNL 1352
            |                             .|..||:...|     |:|...|
  Fly   134 H-----------------------------KEFIQLVAGQD-----RVTLKVR------------ 152

  Fly  1353 AKENGGLSARPNFGGKRLSGVEELSMSATSDIYSTSEAEGVTSVISQSHSTTSDSQITVRSSPIV 1417
                 |:...|    .|....|.||.|... :.|.|.....:|...:....:.|..:.:..:|..
  Fly   153 -----GVGMLP----VRDLPEERLSWSVVK-LPSVSGTPSESSFKGERRGASRDISVVLHVAPRT 207

  Fly  1418 LDKLAVCR----------HCHKNCQQSGPGGARPGGG-GGVNNSSSTPVLLCNSLKVQHSQSSPN 1471
            ...|.:|:          ...|:...:...|.|||.. ..||:...:.||...::.|..|.|..:
  Fly   208 KLGLGICKGPEWKPGIFVQFTKDRSVAREAGLRPGDQILSVNSIDFSDVLFSEAVAVMKSSSKLD 272

  Fly  1472 RCCKLSNGIAGATEMANPKNSNRTGTGTGSVTSMSSSTITGELSSKVVASSSRRETGDTESDVAQ 1536
            ...:.:.|.             ....|..|..:.|:|::||:.|.....:.|:|.|
  Fly   273 MVVRTAAGC-------------DLFPGESSGYNSSASSVTGDQSPCWADAKSKRLT--------- 315

  Fly  1537 LITDEISQSQSEATDDSVGAMPNSSRSAGEGNPVITGSRLRHLDPPVSVSSLPNGHCSAGVGGGS 1601
                               |:...|.:.|.|               ..:||.|        |.||
  Fly   316 -------------------AVREESGAGGGG---------------CGLSSAP--------GAGS 338

  Fly  1602 PKPLPPPRRTRVVAQMCQEPPRPKANQQVKAIVTITETARIMRSSPTKGSGSGSATGTGSVGGSP 1666
            |.   ..:...|..||            .|.|:.:||....:.::....:|..|.:|:||.|..
  Fly   339 PN---WSQGVEVHKQM------------NKTIIKLTENGTSINNTYIASTGGSSVSGSGSTGSG- 387

  Fly  1667 AKYAACHCRCTPEDFTHAQLSPDKMEHQTCKLLESPKQTTTTLEQKQ-EDEQLSLMLIGLAQ-LA 1729
                      |......:|.:|           .:|.:.:||:::.. .....:...|||:. .|
  Fly   388 ----------TSGRSQQSQSNP-----------SNPSRNSTTMKRSHLRPVNSAGSGIGLSSGSA 431

  Fly  1730 PAATLCGQERIPKEENSTPTIAVVPPTPDSVLTKTSTHVWDNSGCSSNGGGTSTTSTATTTTKQP 1794
            .:|...|..............|..||.|..           |.|.:::|...|:.|:|.|...:.
  Fly   432 GSAGSAGSSGSGSRSGGVIAPAPAPPPPAM-----------NEGANASGSVGSSLSSAITEELKK 485

  Fly  1795 RQAIIENIPEDSCDESPLDEEPPYRPMSSALRRFGTMSSLEKLPSDDR-MDEADELDDDLDSFKP 1858
            |:            |....::...|                  .:.|| .|....:|..|
  Fly   486 RK------------EKQQQQQHQQR------------------HNRDRDRDGNGNVDRQL----- 515

  Fly  1859 NGHDGNSPQNEEDDEDADSERALVQNDLGASSSSGVIVN--GEGLASGAWTNRAGAYVSDKMSFF 1921
            .||:||........:.:..:||.|.........|..|.|  |.|.|.||..:...|....
  Fly   516 TGHNGNGGHRSSVGQVSHRQRANVAGVAATLQGSERISNLTGGGGAGGAGGSNGAAGAGG----- 575

  Fly  1922 EESRAFIDKYLGRWNAGDAQQQHQ---QGTASETDEQMDECTSGATSGEEVWGTPTS------GG 1977
            ::..|.:|::         ::.||   :....|::.::......:.:...::|...|      ||
  Fly   576 DQHTALMDEF---------KRAHQRMFRNGFHESEHKLSSLGKSSLADRSLYGREMSLLRVKNGG 631

  Fly  1978 DNDDQDLQLINSENTHSSPTKSSTSLNDDDDTELMMDELLMAPPMTASTIRGLLPRFYRRRLEPL 2042
            ..        ..|.:...||....|:.              .|.:|.||        |:.|.|.|
  Fly   632 SG--------GGEGSGVMPTMRPVSMG--------------RPLVTMST--------YQERGETL 666

  Fly  2043 FEEETESDEE--KTQQDSDD------IKKGEATTNGHYLEDSAG----SSSDSESVPPAPPLVPR 2095
            .......||.  :...:|::      .:....|.|.:.|:...|    :.:.|..:||.||....
  Fly   667 KRTSIMPDESCYRNSINSNNNNGFSRNRSNSNTNNNNRLQSQNGVNPANGNGSPELPPPPPQFAN 731

  Fly  2096 P---VVPDREEDP-------SAEGQQENLAMEDQEDLHSSVERL------LPNLATSAMGPRPLL 2144
            |   .:|.:...|       :..|....|.       :.|:.::      :.:.:.|..|.||
  Fly   732 PQPKQMPPQHIKPMTGNAAANGSGSANGLG-------NGSLAKVRQPMSPMRSASISVGGFRP-- 787

  Fly  2145 TTRLLPTTAIDPQP--PAVLVASSCEYLLDQRPSSVPGRDLAGGS-------IGTTTM------- 2193
                 |.|   |||  .||.:.||      |...||.|||:|...       :||.|:
  Fly   788 -----PAT---PQPDYDAVQIRSS------QGSESVSGRDVATSQQQRRTLRLGTVTIGEYGDQR 838

  Fly  2194 -TSSRPT 2199
             |..|.|
  Fly   839 TTGKRET 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PsGEF	NP_996333.4	DUF4799	<102..209	CDD:292674
		C2	286..>381	CDD:278593
		PDZ_signaling	644..716	CDD:238492
		RhoGEF	831..1000	CDD:295373
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	23/106 (22%)
		PDZ_signaling	197..276	CDD:238492	15/78 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900