DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and AT1G18160

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_173254.2	Gene:	AT1G18160 / 838395	AraportID:	AT1G18160	Length:	992	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	145/557 - (26%)
Similarity:	226/557 - (40%)	Gaps:	165/557 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 SYYQLLLA-ENP-----------DNGVGFPGRGTAVRFNMSSRSRSRRCSSSGS----SSSSKPP 323
            |.|.:..| |||           ::||..|.       |:.|...|....::|.    :.|:...
plant   481 SQYMIDAAKENPQLAQKLHDVLLESGVVAPR-------NLFSEVYSESMEATGEIKSVAESNDEK 538

  Fly   324 SSSSGNHRQGRPPRISQDDRSNSAPNVCINNIRSVTSEVQRSLIMQARPPLPHP----------- 377
            ....|..:|||       ::||..|                   ::..||||.|
plant   539 GKDFGTIQQGR-------NQSNLGP-------------------VRFLPPLPRPQSKAITHDLRE 577

  Fly   378 ------------CT--DHSNSTQASPTSTLKHNRP----------------RARSADESNKNLLL 412
                        |.  .||:|:.:..::....|.|                .|:||:..:..|.|
plant   578 HSGSGLGHLSEHCNIDGHSDSSHSETSTDYPRNVPVAVAAAAVVASSMVVAAAKSANSDSSTLEL 642

  Fly   413 RDA------------------------------------------------KSSEEN-------- 421
            ..|                                                :||:.:
plant   643 SAAAAAAVMATAAAVSRQFELDSLSNGDAGSGGLHGVDSGGERISDRSIGNESSKSDAAIDDVAE 707

  Fly   422 WNILAEEILIGPRIGSGSFGTVYRAHWHG-PVAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNI 485
            ..||.|||.:..|||.||:|.|||..||| .||||....:..:...|:.|::||.|:::.||.||
plant   708 CEILWEEITVAERIGLGSYGEVYRGDWHGTAVAVKKFIDQDITGEALEEFRSEVRMMRRLRHPNI 772

  Fly   486 LLFMGCVSK-PSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKN--IIHR 547
            :||||.|:: |:|:|||::....|||:.:|....:......:.:....|:||:|||:.|  |:||
plant   773 VLFMGAVTRPPNLSIVTEFLPRGSLYRLIHRPNNQLDERKRLRMALDAARGMNYLHSCNPVIVHR 837

  Fly   548 DLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVY 612
            ||||.|:.:.::..||:.||||:..|.  |....:....|:..||||||:|.:   |...:.|||
plant   838 DLKSPNLLVDKNWVVKVCDFGLSRMKV--STYLSSKSTAGTAEWMAPEVLRNE---PADEKCDVY 897

  Fly   613 AFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRP 677
            ::|::::||.....|:|.: |..|::..||       ....|.|.|:.:.....|.|:...:..|
plant   898 SYGVILWELFTLQQPWGKM-NPMQVVGAVG-------FQHRRLDIPEFVDPGIADIIRKCWQTDP 954

  Fly   678 LFRPLLNMLENMLRTLPKIHRSASEPNLTQSQLQNDE 714
            ..||....:.:.|:.|.|..:.|:.|  :.|.|..||
plant   955 RLRPSFGEIMDSLKQLQKPIQRAAVP--SSSALTTDE 989

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	90/255 (35%)
AT1G18160	NP_173254.2	EDR1	154..359	CDD:373038
AT1G18160	NP_173254.2	STKc_MAP3K-like	721..967	CDD:270901	90/258 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910