DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and AT5G58950

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_568893.1	Gene:	AT5G58950 / 836012	AraportID:	AT5G58950	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	458	Identity:	128/458 - (27%)
Similarity:	209/458 - (45%)	Gaps:	71/458 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   309 RRCSSSGSSSSSKPPSSSSGNHRQGRPPRISQDD----RSNSAPNVCINNIRSVTSEVQRS---L 366
            :|.|||.|:|||.|...||.:...|....:...|    .|....|...:..|||:...|.:   :
plant    47 QRSSSSSSASSSDPKLVSSNSQTTGDTSSLEAADVYVVDSEIQTNPVTHKQRSVSPSPQMAVPDV 111

  Fly   367 IMQARP-----PLPH-----------PCTDHSNS------TQASPTSTLK-----HNRPRARSAD 404
            ..:||.     ..||           |...|.||      ...||:..::     ..:.|.:|..
plant   112 FKEARSERKRFSTPHPRRVESEKGMKPKLSHKNSFDKRSFNLRSPSGPIRDLGTLRIQERVKSKK 176

  Fly   405 ESNKNLLLRD------AKSSEENWNILAEEILIGPRIGSGSFGTVYRAHWHG-----PVAVKTLN 458
            ::..:.|..:      |..:.|.:.:...::..|.:...|.:..:|    ||     .||||.:.
plant   177 DTGWSKLFDNTGRRVSAVEASEEFRVDMSKLFFGLKFAHGLYSRLY----HGKYEDKAVAVKLIT 237

  Fly   459 VKTPSP-----AQLQ-AFKNEVAMLKKTRHCNILLFMGCVSKPSL-AIVTQWCEGSSLYKHVHVS 516
            |.....     |:|: .|..||.:|.:..|.|::.|:|....|.: .::||:....||...:|..
plant   238 VPDDDDNGCLGARLEKQFTKEVTLLSRLTHPNVIKFVGAYKDPPVYCVLTQYLPEGSLRSFLHKP 302

  Fly   517 ETK-FKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEK 580
            |.: ..|..||:....:|:||:|:|::.|||||||..|:.:.|:..:||.|||:|..:...  :.
plant   303 ENRSLPLKKLIEFAIDIARGMEYIHSRRIIHRDLKPENVLIDEEFHLKIADFGIACEEEYC--DM 365

  Fly   581 QANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGL 645
            .|:.| |:..|||||:|:.:   |:..::|||:||:|::|::|..:||..: |..|..|.|....
plant   366 LADDP-GTYRWMAPEMIKRK---PHGRKADVYSFGLVLWEMVAGAIPYEDM-NPIQAAFAVVHKN 425

  Fly   646 LRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTLPKIHRSASEPNLTQSQL 710
            :||   .:..|.|.|:|.|.|.|....|..||.|..::.:||....:|.:    ....||:.|::
plant   426 IRP---AIPGDCPVAMKALIEQCWSVAPDKRPEFWQIVKVLEQFAISLER----EGNLNLSSSKI 483

  Fly   711 QND 713
            ..|
plant   484 CKD 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	86/264 (33%)
AT5G58950	NP_568893.1	STKc_MAP3K-like	214..463	CDD:270901	86/262 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910