DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and AT5G50000

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_199811.1	Gene:	AT5G50000 / 835064	AraportID:	AT5G50000	Length:	385	Species:	Arabidopsis thaliana

Alignment Length:	379	Identity:	96/379 - (25%)
Similarity:	168/379 - (44%)	Gaps:	77/379 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 NIRSVTSEVQRSLIMQARPPLPHPCTDHSNSTQASPTSTLKHNRPRARSADESNKNLLLRDAKSS 418
            :::|:..:::|.|                     |...||:.|:.:    ||.:...:.....:|
plant    15 DLKSLDEQLERHL---------------------SRALTLEKNKKK----DEEDTTAVAIGGSAS 54

  Fly   419 EE-----------------NWNILAEEILIGPRIGSGSFGTVYRAHWHG-PVAVKTLNVKTP--- 462
            ..                 .|.|...:::|...:..|:||||:|..:.| .||||.|:....
plant    55 SSPVTLNGGGFVGKRKQRLEWEIDPSKLIIKTVLARGTFGTVHRGIYDGQDVAVKLLDWGEEGHR 119

  Fly   463 SPAQLQA----FKNEVAMLKKTRHCNILLFMGCVSKPS-----------------LAIVTQWCEG 506
            |.|::.:    |..|||:..|..|.|:..|:|.....|                 ..:|.::..|
plant   120 SEAEIVSLRADFAQEVAVWHKLDHPNVTKFIGATMGASGLQLQTESGPLAMPNNICCVVVEYLPG 184

  Fly   507 SSLYKH-VHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLA 570
            .:|..: :.....|.....::.:...:|:|:.|||::.|:|||:|:.|:.|.:..:|||.|||:|
plant   185 GALKSYLIKNRRRKLTFKIVVQLALDLARGLSYLHSQKIVHRDVKTENMLLDKTRTVKIADFGVA 249

  Fly   571 TAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKD 635
            ..:.  |........||::.:|||||:..   |||:.:.|||:|||.::|:....:||..:: ..
plant   250 RVEA--SNPNDMTGETGTLGYMAPEVLNG---NPYNRKCDVYSFGICLWEIYCCDMPYPDLT-FS 308

  Fly   636 QILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENM 689
            ::...|.|..||||:.:.   .|.||..:.:.|....|..||....::.|||::
plant   309 EVTSAVVRQNLRPDIPRC---CPSALAAVMKRCWDANPDKRPEMDEVVPMLESI 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	81/277 (29%)
AT5G50000	NP_199811.1	STKc_MAP3K-like	88..356	CDD:270901	80/276 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910