DRSC/TRiP Functional Genomics Resources

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Protein Alignment Raf and AT5G49470

DIOPT Version :9

Sequence 1:NP_001096867.3 Gene:Raf / 31221 FlyBaseID:FBgn0003079 Length:739 Species:Drosophila melanogaster
Sequence 2:NP_974914.2 Gene:AT5G49470 / 835007 AraportID:AT5G49470 Length:831 Species:Arabidopsis thaliana


Alignment Length:519 Identity:135/519 - (26%)
Similarity:230/519 - (44%) Gaps:130/519 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   295 GTAVRFNMSSRSRSRRCSSSGSSSSSKPPSSSS-----------------GNHRQGRP------- 335
            |..:|.:..:.::..|.||..|..:|..|.:.:                 ||.|:|..       
plant   339 GVFLRSDEKASTKPFRDSSDESDGNSVVPKTLTSKAEEWMVKKGLSWPWKGNEREGLEGRRSHSV 403

  Fly   336 -PRISQDDRSNSAPNVCINNIRSVTSEVQ--RSLIMQARPPLPHPCTDHSNSTQASPTSTLKHNR 397
             |.:..:.:...|..  .|:..||.||.|  .|:...:..|:.:    .|:|...:.||:     
plant   404 WPWVRNEQQKQQAYQ--SNSNHSVKSESQACESIKASSNEPMGY----WSSSVNVNSTSS----- 457

  Fly   398 PRARSADESNKNLLLR-DAKSSEENWNILAEEILIGPRIGSGSFGTVYRAHWHG-PVAVKTLNVK 460
              :.|...::.:::.: |..|...::.||.|::.||.:||.||.||||...|.| .||||..:.:
plant   458 --SSSCGSTSSSVMNKVDMDSDCLDYEILWEDLTIGEQIGQGSCGTVYHGLWFGSDVAVKVFSKQ 520

  Fly   461 TPSPAQLQAFKNEVAMLKKTRHCNILLFMGCVSKPS-LAIVTQW--------------------- 503
            ..|...:.:|:.||:::|:.||.|:|||||.|:.|. |.|||::                     
plant   521 EYSEEIITSFRQEVSLMKRLRHPNVLLFMGAVTSPQRLCIVTEFLPRFGLITLANITLPFVLFEL 585

  Fly   504 ---------------------CEGS---------SLYKHVHVSETKFKLNTLIDIGRQV------ 532
                                 |.|:         |::..:... ..:.|::||.:...|      
plant   586 RGQNSDLPYQITFAVEVSSVCCRGTRQNWIGGDVSIWPRIFYL-AYYSLDSLIQLLYLVYNMLHI 649

  Fly   533 --------AQGMDYLH--AKNIIHRDLKSNNIFLHEDLSVKIGDFGLATAK-----TRWSGEKQA 582
                    |:||:|||  ...||||||||:|:.:.::.:||:.||||:..|     |..:|.   
plant   650 FLTYFFAQARGMNYLHHCTPPIIHRDLKSSNLLVDKNWTVKVADFGLSRIKHETYLTTKTGR--- 711

  Fly   583 NQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLR 647
                |:..||||||:|.:..:.   :||||:||::::||:.|.:|:..: |..|::..|  |.:.
plant   712 ----GTPQWMAPEVLRNEAADE---KSDVYSFGVILWELVTEKIPWESL-NAMQVIGAV--GFMN 766

  Fly   648 PDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTLPKIHRSASEPNLTQSQLQ 711
            ..:...::..||.:. |.|.|....|:|||.|:.::..|..:.|......::|...::..|.|:
plant   767 QRLEVPKNVDPQWIS-LMESCWHSEPQDRPSFQEIMEKLRELQRKYTIQFQAARAASIENSALK 829

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RafNP_001096867.3 RBD_RAF 142..212 CDD:340514
C1_Raf 221..269 CDD:410361
STKc_Raf 435..687 CDD:270964 96/325 (30%)
AT5G49470NP_974914.2 PAS 100..210 CDD:279347
PAS 109..210 CDD:238075
Pkinase_Tyr 488..804 CDD:285015 98/330 (30%)
STKc_MAP3K-like 494..804 CDD:270901 96/324 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR44329
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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