DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Raf and AT5G11850

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_196746.2	Gene:	AT5G11850 / 831058	AraportID:	AT5G11850	Length:	880	Species:	Arabidopsis thaliana

Alignment Length:	458	Identity:	135/458 - (29%)
Similarity:	213/458 - (46%)	Gaps:	72/458 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 CANRVPMLCQPFPMDSYYQLLLAENPDNGVGFPGRGTAVRFNMSSRSRSRRCSSSGSSSSSKPPS 324
            ||.:|.:     ...|.|.:..|:||:    |..:..||..               .|.:|.||.
plant   451 CAQKVKV-----KNVSKYVISAAKNPE----FAQKLHAVLL---------------ESGASPPPD 491

  Fly   325 SSSG-NHRQGRPPRISQDDRSNSAPNVCINNIRSVTSEVQRSLIMQARPPLPHPCT--------- 379
            .... |....|...:.|:.|..|: |..::.|.....:|...|....|.|......
plant   492 LFMDINPHNLRGKNLLQELRQESS-NSMVSGIPCYPEKVAEQLRESERNPTAESYQQSVEVDLSM 555

  Fly   380 ----DHSNSTQASPTSTLKHNRPRARSA-----DESNKNLLLRDAKSSEENWNILAEEILIGPRI 435
                |..|:.:||.:..::.......||     |:....||...||     |.|:.|::.||.||
plant   556 KRNFDLDNTGKASSSENMEVGTADGESAVCDSHDQGINPLLGEAAK-----WEIMWEDLQIGERI 615

  Fly   436 GSGSFGTVYRAHWHG-PVAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNILLFMGCVSK-PSLA 498
            |.||:|.||||.|:| .||||....:..|...|..||:|:.::.:.||.|::||||.|:: |:.:
plant   616 GIGSYGEVYRAEWNGTEVAVKKFLDQDFSGDALTQFKSEIEIMLRLRHPNVVLFMGAVTRPPNFS 680

  Fly   499 IVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKN--IIHRDLKSNNIFLHEDLS 561
            |:|::....|||:.:|....:......:.:...||:||:|||..:  ::||||||.|:.:.::..
plant   681 ILTEFLPRGSLYRLLHRPNHQLDEKRRMRMALDVAKGMNYLHTSHPTVVHRDLKSPNLLVDKNWV 745

  Fly   562 VKIGDFGLATAK--TRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAE 624
            ||:.||||:..|  |..|.:..|..|.    ||||||:|.:   |.:.:.|||:||::::||...
plant   746 VKVCDFGLSRMKHHTYLSSKSTAGTPE----WMAPEVLRNE---PANEKCDVYSFGVILWELATS 803

  Fly   625 CLPYGHISNKDQILFMVG---RGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNML 686
            .:|:..: |..|::..||   |.|..||      |....:.::..:|.:..|..||.|..|:..|
plant   804 RVPWKGL-NPMQVVGAVGFQNRRLEIPD------DIDLTVAQIIRECWQTEPHLRPSFTQLMQSL 861

  Fly   687 ENM 689
            :.:
plant   862 KRL 864

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361	3/8 (38%)
		STKc_Raf	435..687	CDD:270964	91/260 (35%)
AT5G11850	NP_196746.2	EDR1	140..344	CDD:291079
		Pkinase_Tyr	609..861	CDD:285015	94/265 (35%)
		STKc_MAP3K-like	615..861	CDD:270901	91/259 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910