DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and AT4G18950

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_567568.1	Gene:	AT4G18950 / 827630	AraportID:	AT4G18950	Length:	459	Species:	Arabidopsis thaliana

Alignment Length:	259	Identity:	80/259 - (30%)
Similarity:	133/259 - (51%)	Gaps:	19/259 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   441 GTVYRAHWHG-PVAVKTLNVKTPS-PAQLQAFKNEVAMLKKTRHCNILLFMGCVSKPS-LAIVTQ 502
            ||...|.|.| .||||.|:.:..| ..|::.|.:|:|:|::.||.||:.|:|.|::.: :.|||:
plant   169 GTYCMAMWRGIQVAVKKLDDEVLSDDDQVRKFHDELALLQRLRHPNIVQFLGAVTQSNPMMIVTE 233

  Fly   503 WCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLH---AKNIIHRDLKSNNIFLHEDLSVKI 564
            :.....| :.:...:.:.|..|.:.....:|:||.|||   ...||||||:.:||...:...:|:
plant   234 YLPRGDL-RELLKRKGQLKPATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNILRDDSGHLKV 297

  Fly   565 GDFG---LATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECL 626
            .|||   |.|.|.    :|.......|..::||||...:|   |..::||::|.:::.|::...:
plant   298 ADFGVSKLVTVKE----DKPFTCQDISCRYIAPEVFTSEE---YDTKADVFSFALIVQEMIEGRM 355

  Fly   627 PYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENML 690
            |:....:.:......|:.  ||.......:.|..||.|.|:|....|..||.||.::..||::|
plant   356 PFAEKEDSEASEAYAGKH--RPLFKAPSKNYPHGLKTLIEECWHEKPAKRPTFREIIKRLESIL 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	77/254 (30%)
AT4G18950	NP_567568.1	ANK repeat	42..73	CDD:293786
		Ank_2	47..134	CDD:372319
		ANK repeat	75..106	CDD:293786
		ANK repeat	108..133	CDD:293786
		STKc_MAP3K-like	176..413	CDD:270901	74/246 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100006
Panther	1	1.100	-	-	O	PTHR44329
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000