DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and AT3G59830

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_191542.2	Gene:	AT3G59830 / 825152	AraportID:	AT3G59830	Length:	477	Species:	Arabidopsis thaliana

Alignment Length:	482	Identity:	122/482 - (25%)
Similarity:	199/482 - (41%)	Gaps:	107/482 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 RGTAVRFNMSS--RSRSRRCS--------------SSGSSSSSKP----PSSSSGNHRQGRPPRI 338
            ||.:.:|:..|  |:.||:.:              |.|..||..|    |.|.|..      |.:
plant    10 RGISRQFSTGSMRRTLSRQFTRQNSLDPRRNNMRFSFGRQSSLDPIRRSPESLSCE------PHM 68

  Fly   339 SQDDRSNSAPNVC-------INNIRSVTSE--VQRSLIMQARPPLPH--PCTDHSNSTQASPTST 392
            |..:..:|...:.       :|.:..:.:|  ...|:.:..|..| |  .|..|.:..:     .
plant    69 SVPENLDSTMQLLFMASKGDVNGVEELLNEGIDVNSIDLDGRTAL-HIASCEGHYDVVK-----V 127

  Fly   393 LKHNRPRARSADESNKNLLLRDAK--SSEENWNIL----------------------AEEILIGP 433
            |...|....:.|.......: |||  .:.|.:|:|                      ..|..:.|
plant   128 LLSRRANIDARDRWGSTAAV-DAKYYGNVEVYNLLKARGAKAPKTRKTPMTVGNPKEVPEYELNP 191

  Fly   434 ------RIGSGSFGTVYRAHWHGP-VAVKTLNVKTPS-PAQLQAFKNEVAMLKKTRHCNILLFMG 490
                  ::...|.||...|.|:|. |:||..:..:.| |.::.||.||:.:|.|.||.||:.|:|
plant   192 LELQVRKVDGISKGTYQVAKWNGTRVSVKIFDKDSYSDPERVNAFTNELTLLAKARHPNIVQFVG 256

  Fly   491 CVSK--PSLAIVTQWCEGS-SLY--KHVHVSETKFKLNTLIDIGRQVAQGMDYLH---AKNIIHR 547
            .|::  |.:.:|....:|. |:|  |...:|.:| .|...:||    |:||:|||   ...|||.
plant   257 AVTQNLPMMIVVECNPKGDLSVYLQKKGRLSPSK-ALRFALDI----ARGMNYLHECKPDPIIHC 316

  Fly   548 DLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQAN------QPTGSILWMAPEVIRMQELNPYS 606
            :|...||.|.....:||..|||  .|....||..|.      |...|..::|||:.:.:   .:.
plant   317 ELMPKNILLDRGGQLKISGFGL--IKLSKIGEDSAKVVNHEAQIDKSNYYIAPEIYKDE---VFD 376

  Fly   607 FQSDVYAFGIVMYELLAECLPYGHISNKDQI---LFMVGRGLLRPDMSQVRSDAPQALKRLAEDC 668
            .::||::||:::|| |.|.:...|....:::   :.:.|:   ||.:.......|..||.|.|:|
plant   377 KRADVHSFGVILYE-LTEGVSLFHPKPPEEVAESICIEGK---RPTIRTKSKSYPPELKELIEEC 437

  Fly   669 IKYTPKDRPLFRPLLNMLENMLRTLPK 695
            .......||:|..::..|:.::....|
plant   438 WHPEISVRPIFSEIIIRLDKIVTNCSK 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	83/270 (31%)
AT3G59830	NP_191542.2	Ank_2	80..167	CDD:403870	17/93 (18%)
		ANK repeat	80..106	CDD:293786	3/25 (12%)
		ANK repeat	108..139	CDD:293786	7/36 (19%)
		ANK repeat	141..166	CDD:293786	6/25 (24%)
		PKc_like	202..455	CDD:419665	83/266 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44329
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100