DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and AT3G01490

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_186798.1	Gene:	AT3G01490 / 821136	AraportID:	AT3G01490	Length:	411	Species:	Arabidopsis thaliana

Alignment Length:	374	Identity:	106/374 - (28%)
Similarity:	183/374 - (48%)	Gaps:	50/374 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 NIRSVTSEVQRSL----IMQARPPLPHPCTDHSNSTQASPTS----TLKHNRPRA----RSADES 406
            :::|:..::||.|    .|:.|..|... .|:.|:|:.:..:    .|...||..    .:.:.|
plant    20 DLKSLDEQLQRHLSKAWTMEKRKSLSDG-EDNVNNTRHNQNNFGHRQLVFQRPLLGGGYSNNNNS 83

  Fly   407 NKNLLLR--DAKSSEENWNILAEEILIGPRIGSGSFGTVYRAHWHG-PVAVKTLNVKTP---SPA 465
            :||.::|  :.:.|...|.|...:::|...|..|:||||:|..:.| .||||.|:....   |.|
plant    84 SKNDIIRSTEVEKSRREWEIDPSKLIIKSVIARGTFGTVHRGIYDGQDVAVKLLDWGEEGHRSDA 148

  Fly   466 QL----QAFKNEVAMLKKTRHCNILLFMGC---------------VSKPS--LAIVTQWCEGSSL 509
            ::    .||..|||:..|..|.|:..|:|.               :..||  ..:|.::|.|.:|
plant   149 EIASLRAAFTQEVAVWHKLDHPNVTKFIGAAMGTSEMSIQTENGQMGMPSNVCCVVVEYCPGGAL 213

  Fly   510 YKH-VHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATAK 573
            ... :.....|.....:|.:...:|:|:.|||::.|:|||:|:.|:.|.:..::||.|||:|..:
plant   214 KSFLIKTRRRKLAFKVVIQLSLDLARGLSYLHSQKIVHRDVKTENMLLDKSRTLKIADFGVARLE 278

  Fly   574 TRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQIL 638
            .  |........||::.:|||||:..   :||:.:.|||:|||.::|:....:||..:| ..::.
plant   279 A--SNPNDMTGETGTLGYMAPEVLNG---SPYNRKCDVYSFGICLWEIYCCDMPYPDLS-FSEVT 337

  Fly   639 FMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLE 687
            ..|.|..|||::.:.   .|.:|..:.:.|....|:.||....::.|||
plant   338 SAVVRQNLRPEIPRC---CPSSLANVMKRCWDANPEKRPEMEEVVAMLE 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	83/277 (30%)
AT3G01490	NP_186798.1	STKc_MAP3K-like	114..382	CDD:270901	82/276 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910