DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and AT2G43850

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_181913.3	Gene:	AT2G43850 / 818989	AraportID:	AT2G43850	Length:	479	Species:	Arabidopsis thaliana

Alignment Length:	450	Identity:	120/450 - (26%)
Similarity:	193/450 - (42%)	Gaps:	69/450 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 RGTAVRFN---MSSRSRSRRCSSSGSSSSSKPPSS---------------SSGNHR-------QG 333
            |.|.:||:   .||....|| |...|.|..:|..|               |.|:.|       :|
plant    38 RRTNMRFSFGRQSSLDPIRR-SPDSSKSDDEPHMSVPENLDSTMQLLFMASKGDVRGIEELLDEG 101

  Fly   334 RPPR-ISQDDRSNSAPNVCINNIRSVTSEVQRSLIMQARPPLPHPCTDHSNSTQASPTSTL---- 393
            .... |..|.|:......|..::..|.:.:.|...:.||        |...||.|:.....
plant   102 IDVNSIDLDGRTALHIAACEGHLGVVKALLSRRANIDAR--------DRWGSTAAADAKYYGNLD 158

  Fly   394 KHNRPRARSA--DESNKN--LLLRDAKSSEENWNILAEEILIGPRIGSGSFGTVYRAHWHGP-VA 453
            .:|..:||.|  .::.|.  .:....:..|...|.|..::.....|..|::..   |.|:|. |:
plant   159 VYNLLKARGAKVPKTRKTPMTVSNPREVPEYELNPLEVQVRKSDGISKGAYQV---AKWNGTRVS 220

  Fly   454 VKTLNVKTPS-PAQLQAFKNEVAMLKKTRHCNILLFMGCVSK--PSLAIVTQWCEGS-SLY--KH 512
            ||.|:..:.| |.::.||::|:.:|:|.||.|::.|:|.|::  |.:.:|....:|. |:|  |.
plant   221 VKILDKDSYSDPERINAFRHELTLLEKVRHPNVIQFVGAVTQNIPMMIVVEYNPKGDLSVYLQKK 285

  Fly   513 VHVSETKFKLNTLIDIGRQVAQGMDYLH---AKNIIHRDLKSNNIFLHEDLSVKIGDFG-LATAK 573
            ..:|.:| .|...:||    |:||:|||   ...|||.|||..||.|.....:||..|| :..:|
plant   286 GRLSPSK-ALRFALDI----ARGMNYLHECKPDPIIHCDLKPKNILLDRGGQLKISGFGMIRLSK 345

  Fly   574 TRWSGEKQANQPTG---SILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKD 635
            ......|.||....   |..::||||.: .|:  :..:.|.::||:::|| :.|.:|..|....:
plant   346 ISQDKAKVANHKAHIDLSNYYIAPEVYK-DEI--FDLRVDAHSFGVILYE-ITEGVPVFHPRPPE 406

  Fly   636 QILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTLPK 695
            ::..|:.....||.........|..:|.|.|.|.......||.|..::..|:.::....|
plant   407 EVARMMCLEGKRPVFKTKSRSYPPDIKELIEKCWHPEAGIRPTFSEIIIRLDKIVANCSK 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	81/265 (31%)
AT2G43850	NP_181913.3	Ank_2	82..170	CDD:372319	20/95 (21%)
		ANK repeat	82..108	CDD:293786	4/25 (16%)
		ANK repeat	110..141	CDD:293786	7/38 (18%)
		ANK repeat	143..168	CDD:293786	6/24 (25%)
		PKc_like	204..457	CDD:389743	81/264 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44329
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100