DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and AT2G42640

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_181792.4	Gene:	AT2G42640 / 818864	AraportID:	AT2G42640	Length:	781	Species:	Arabidopsis thaliana

Alignment Length:	441	Identity:	116/441 - (26%)
Similarity:	191/441 - (43%)	Gaps:	79/441 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 RFHQRCANRVPMLCQPFPMDSYYQL-LLAEN--PDNGVGFPGRGTAVRFNMSSRSR-SRRCSSSG 315
            |.:.||.| .|.|.......:..|. ||.|.  .|:....|.......|.:.|... |..||:..
plant   405 RTNGRCMN-TPDLNNDIARATMMQSDLLKERGVDDSSPYSPDEKNVSGFQLDSHDLVSGECSTVY 468

  Fly   316 SSSSSKPPSSSSGNHRQGRPPRISQDDRSNSAPNVCINNIRSVTSEVQRSLIMQARPPLPHPCTD 380
            ...|...|||.       |..:|...:||..:|    ..|..:.:||..|.:.|.:|.||.
plant   469 PRKSISLPSSP-------RSYQIQLSERSEHSP----QEISHIWNEVLESPMFQNKPLLPF---- 518

  Fly   381 HSNSTQASPTSTLKHNRPRARSADESNKNLLLRDAKSSEENWNILAEEILIGPRIGSGSFGTVYR 445
                                                   |.|||...::.:|..:|||:.|.|.|
plant   519 ---------------------------------------EEWNIDFSKLKVGASVGSGTSGVVCR 544

  Fly   446 AHWH-GPVAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNILLFMG-CVSKPSLAIVTQWCEGSS 508
            ..|: ..||:|....:..:...::.|.||:::|.:.:|.|::|.:| |...|.|::||::....|
plant   545 GVWNKTEVAIKIFLGQQLTAENMKVFCNEISILSRLQHPNVILLLGACTKPPQLSLVTEYMSTGS 609

  Fly   509 LYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATAK 573
            ||..:...:.:......:.|..::.:|:.|:|...|:||||.|.|..|::.: |||.||||:
plant   610 LYDVIRTRKKELSWQRKLKILAEICRGLMYIHKMGIVHRDLTSANCLLNKSI-VKICDFGLS--- 670

  Fly   574 TRWSGEK-QANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQI 637
            .|.:|.. :..:..|:..|||||:||.:   |.:.:||:::||::|:||.....|:..:..:..|
plant   671 RRMTGTAVKDTEAAGTPEWMAPELIRNE---PVTEKSDIFSFGVIMWELSTLSKPWKGVPKEKVI 732

  Fly   638 LFMVGRGLLRPDMSQVRSDAPQA-LKRLAEDCIKYTPKDRPLFRPLLNMLE 687
            ..:...|        .|...|:. |::|..||.. .|:.||..:.:|:.|:
plant   733 HIVANEG--------ARLKIPEGPLQKLIADCWS-EPEQRPSCKEILHRLK 774

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361	6/13 (46%)
		STKc_Raf	435..687	CDD:270964	76/255 (30%)
AT2G42640	NP_181792.4	EDR1	125..316	CDD:405130
AT2G42640	NP_181792.4	STKc_MAP3K-like	534..773	CDD:270901	76/254 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44329
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010