DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and AT2G31800

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_180739.2	Gene:	AT2G31800 / 817737	AraportID:	AT2G31800	Length:	476	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	122/484 - (25%)
Similarity:	194/484 - (40%)	Gaps:	110/484 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 NGVGFPGRGTAVRFNMS------SRSRSRRCS----------SSGSSSSSKP----PSSSSGNHR 331
            |.||...||.:.:|:..      ||..:|:.|          |.|..||..|    |..|:|
plant     3 NVVGQLKRGISRQFSTGSLRRTLSRQFTRQASHDPRRNNMRFSFGRQSSLDPIRRSPDGSNG--- 64

  Fly   332 QGRPPRISQDDRSNSAPNVCINNIRSVTSEVQ---------RSLIMQARPPLPH--PCTDHSNST 385
                |:::..|..::...:.....|.....||         .|:.:..|..| |  .|..|
plant    65 ----PQLAVPDNLDATMQLLFVACRGDVEGVQDLLDEGIDVNSIDLDGRTAL-HIAACEGH---- 120

  Fly   386 QASPTSTLKHNRPRARSADESNK--NLLLRDAK--SSEENWNILAEE------------ILIGPR 434
                ...:|....|..:.|..::  :....|||  .:.:.:|||...            ::..||
plant   121 ----VDVVKLLLTRKANIDARDRWGSTAAADAKYYGNMDVFNILKARGAKVPKTKRTPMVVANPR 181

  Fly   435 -------------------IGSGSFGTVYR-AHWHG-PVAVKTLNVKTPSPAQ-LQAFKNEVAML 477
                               |..|    :|: |.|:| .|:||.|:......:. :.|||:|:.:.
plant   182 EVPEYELNPQELQVRKADGISKG----IYQVAKWNGTKVSVKILDKDLYKDSDTINAFKHELTLF 242

  Fly   478 KKTRHCNILLFMGCVSK-PSLAIVTQWCE----GSSLYKHVHVSETKFKLNTLIDIGRQVAQGMD 537
            :|.||.|::.|:|.|:: ..:.||:::..    ||.|.|...:|..|. |...:||    |:||:
plant   243 EKVRHPNVVQFVGAVTQNVPMMIVSEYHPKGDLGSYLQKKGRLSPAKV-LRFALDI----ARGMN 302

  Fly   538 YLH---AKNIIHRDLKSNNIFLHEDLSVKIGDFGLAT-AKTRWSGEKQANQPT---GSILWMAPE 595
            |||   .:.:||.|||..||.|.....:|:..|||.: ||......|..|...   .|...||||
plant   303 YLHECKPEPVIHCDLKPKNIMLDSGGHLKVAGFGLISFAKLSSDKSKILNHGAHIDPSNYCMAPE 367

  Fly   596 VIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQA 660
            |.: .|:  :....|.|:||:|:||::....|:.....::.:..|...| .||.........||.
plant   368 VYK-DEI--FDRSVDSYSFGVVLYEMIEGVQPFHPKPPEEAVKLMCLEG-RRPSFKAKSKSCPQE 428

  Fly   661 LKRLAEDCIKYTPKDRPLFRPLLNMLENM 689
            ::.|.|:|.......||.|..::..|:.:
plant   429 MRELIEECWDTETFVRPTFSEIIVRLDKI 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	81/266 (30%)
AT2G31800	NP_180739.2	ANK	80..178	CDD:238125	18/106 (17%)
		Ank_2	80..167	CDD:289560	18/95 (19%)
		ANK repeat	107..138	CDD:293786	8/39 (21%)
		ANK repeat	140..165	CDD:293786	6/24 (25%)
		STKc_MAP3K-like	201..454	CDD:270901	81/265 (31%)
		TyrKc	203..454	CDD:197581	80/263 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44329
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100