DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and STY8

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_179361.1	Gene:	STY8 / 816278	AraportID:	AT2G17700	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	317	Identity:	108/317 - (34%)
Similarity:	171/317 - (53%)	Gaps:	24/317 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 DHSNSTQASPTSTLKHNRPRARSADESNKNLL---LRDAKSSEENWNILAEEILIGPRIGSGSFG 441
            |...|.|.| .|..:|        |:|:..|:   :.......:.|.|...::.|..::.|||:|
plant   243 DQPGSKQKS-ISFFEH--------DKSSNELIPACIEIPTDGTDEWEIDVTQLKIEKKVASGSYG 298

  Fly   442 TVYR-AHWHGPVAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNILLFMG-CVSKPSLAIVTQWC 504
            .::| .:....||:|.|.....:...|:.|..||.:::|.||.|::.|:| |...|:|.|||::.
plant   299 DLHRGTYCSQEVAIKFLKPDRVNNEMLREFSQEVFIMRKVRHKNVVQFLGACTRSPTLCIVTEFM 363

  Fly   505 EGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGL 569
            ...|:|..:|..:..|||.||:.:...||:||.|||..||||||||:.|:.:.|...||:.|||:
plant   364 ARGSIYDFLHKQKCAFKLQTLLKVALDVAKGMSYLHQNNIIHRDLKTANLLMDEHGLVKVADFGV 428

  Fly   570 ATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNK 634
            |..:.. ||...|.  ||:..|||||||   |..||:.::||:::.||::|||...:||..::..
plant   429 ARVQIE-SGVMTAE--TGTYRWMAPEVI---EHKPYNHKADVFSYAIVLWELLTGDIPYAFLTPL 487

  Fly   635 DQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLR 691
            ...:.:|.:| |||   ::.......:|.|.|.|....|:.||||..::.||:.:::
plant   488 QAAVGVVQKG-LRP---KIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEMLQQIMK 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	95/253 (38%)
STY8	NP_179361.1	ACT_TyrKc	172..239	CDD:153200
		Pkinase_Tyr	286..535	CDD:285015	95/258 (37%)
		STKc_MAP3K-like	292..535	CDD:270901	94/252 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910