DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and si:ch211-45c16.2

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	XP_017213349.1	Gene:	si:ch211-45c16.2 / 568412	ZFINID:	ZDB-GENE-081105-15	Length:	982	Species:	Danio rerio

Alignment Length:	274	Identity:	90/274 - (32%)
Similarity:	139/274 - (50%)	Gaps:	30/274 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   420 ENWNILAEEILIGPRIGSGSFGTVYRAHWHG-PVAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHC 483
            |.|.:..|||.....:|||:.|.|:...:.. .||:|.:.         :..:.::..|:|.:|.
Zfish   211 EMWEVPFEEISELQWLGSGAQGAVFLGKFRSEEVAIKKVR---------EQKETDIKHLRKLKHP 266

  Fly   484 NILLFMG-CVSKPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHR 547
            ||:.|.| |...|...|:.::|....||:.:.... |.....|:|....:|.||:|||...||||
Zfish   267 NIISFKGVCTQAPCYCIIMEYCAQGQLYEVLRAGR-KITPCLLVDWASGIASGMNYLHLHKIIHR 330

  Fly   548 DLKSNNIFLHEDLSVKIGDFG----LATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQ 608
            ||||.|:.:.::.||||.|||    |:...|:.|.       .|::.||||||||.:   |.|.:
Zfish   331 DLKSPNVLVTQNDSVKISDFGTSKELSDKSTKMSF-------AGTVAWMAPEVIRNE---PVSEK 385

  Fly   609 SDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTP 673
            .|:::||:|::|||...:||..: :...|::.||...|.   ..|.|..|...|.|.:...:..|
Zfish   386 VDIWSFGVVLWELLTGEIPYKDV-DSSAIIWGVGSNSLH---LPVPSTCPDGFKILMKQTWQGKP 446

  Fly   674 KDRPLFRPLLNMLE 687
            ::||.||.:|..|:
Zfish   447 RNRPSFRQILLHLD 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	84/257 (33%)
si:ch211-45c16.2	XP_017213349.1	STKc_MAP3K12_13	226..462	CDD:270961	85/259 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910