DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Raf and Mos

DIOPT Version :9

Sequence 1:	NP_001096867.3	Gene:	Raf / 31221	FlyBaseID:	FBgn0003079	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_610817.1	Gene:	Mos / 36404	FlyBaseID:	FBgn0033773	Length:	364	Species:	Drosophila melanogaster

Alignment Length:	234	Identity:	62/234 - (26%)
Similarity:	102/234 - (43%)	Gaps:	30/234 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   435 IGSGSFGTVYRAHWHG-PVAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNILLFMGCVSKPSLA 498
            :|.|::|||::|.:.. .||||.:..:..|     ...||..:| ...|.||:..:...|.....
  Fly    28 LGRGAYGTVFKAIYRDRSVAVKIIRAQAAS-----TLHNESHLL-NLEHRNIVRLLKLESAADFG 86

  Fly   499 IVTQWC-EGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIF------- 555
            :|...| .|.||.:.|...........||.:  .|...:.|.|::|::|.|:|..||.
  Fly    87 LVIMECPRGQSLQRIVDTLALPLMHRVLITL--DVVAALRYCHSQNVLHLDVKPTNILVALGTKS 149

  Fly   556 ----------LHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSD 610
                      :......|:.|||.:.....:...::.:...|::.:|:||.:|...|..   .||
  Fly   150 SITCNSSKIKVKRSYICKLCDFGSSIEMGEFCAWQEPSVAKGTLRYMSPEALRSDTLTE---ASD 211

  Fly   611 VYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPD 649
            :|:.||.|::|.|..|||..:...:.|.:.|.:..||||
  Fly   212 IYSLGITMWQLQARRLPYHTLDCNETIAYQVVKHELRPD 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	62/234 (26%)
Mos	NP_610817.1	STKc_Mos	19..298	CDD:270881	62/234 (26%)
Mos	NP_610817.1	S_TKc	26..257	CDD:214567	62/234 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445238
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930