DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Raf and Ripk2

DIOPT Version :9

Sequence 1:NP_001096867.3 Gene:Raf / 31221 FlyBaseID:FBgn0003079 Length:739 Species:Drosophila melanogaster
Sequence 2:NP_620402.1 Gene:Ripk2 / 192656 MGIID:1891456 Length:539 Species:Mus musculus


Alignment Length:331 Identity:97/331 - (29%)
Similarity:158/331 - (47%) Gaps:56/331 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   434 RIGSGSFGTVYRAHWHGPVAVKTLNVKTPSPAQLQAFKN----EVAMLKKTRHCNILLFMGCVSK 494
            |..||:..:...|.|...||||.|::.||   .|.:.:|    |..:|.|.|...||..:|..::
Mouse    26 RGASGTVSSARHADWRVRVAVKHLHIHTP---LLDSERNDILREAEILHKARFSYILPILGICNE 87

  Fly   495 PS-LAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIG--------RQVAQGMDYLHAKN--IIHRD 548
            |. |.|||::....||.:.:| .:|::.     ||.        .::|.|::|||..|  ::|.|
Mouse    88 PEFLGIVTEYMPNGSLNELLH-RKTEYP-----DIAWPLRFRILHEIALGVNYLHNMNPPLLHHD 146

  Fly   549 LKSNNIFLHEDLSVKIGDFGLATAKTRW-------SGEKQANQPTGSILWMAPEVIRMQELNPYS 606
            ||:.||.|..:..|||.||||    ::|       |...::....|:|::|.||.....:.:..|
Mouse   147 LKTQNILLDNEFHVKIADFGL----SKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRAS 207

  Fly   607 FQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQ--VRSDAPQ--ALKRLAED 667
            .:.|:|::.::|:|:|:...|:..::|..||::.|.:| .|||.|:  :..|.|.  .:..|.:.
Mouse   208 VKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQG-HRPDTSEENLPFDIPHRGLMISLIQS 271

  Fly   668 CIKYTPKDRPLFRPLLNMLENMLRTL--------------PKIHRSASEPNLTQSQLQNDEFLYL 718
            .....|.:||.|...|..||.:|||.              .||..|:|..:|...::  |..|.:
Mouse   272 GWAQNPDERPSFLKCLIELEPVLRTFEDITFLEAVIQLKKAKIQSSSSTIHLCDKKM--DLSLNI 334

  Fly   719 PSPKTP 724
            |:...|
Mouse   335 PANHPP 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RafNP_001096867.3 RBD_RAF 142..212 CDD:340514
C1_Raf 221..269 CDD:410361
STKc_Raf 435..687 CDD:270964 82/277 (30%)
Ripk2NP_620402.1 STKc_RIP2 20..303 CDD:270928 88/290 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 335..368 2/6 (33%)
CARD_RIP2_CARD3 437..522 CDD:176764
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 519..539
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100006
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.