Protein Alignment Raf and F22B3.8

DIOPT Version :9

• Sequence 1: NP_001096867.3
• Gene: Raf / 31221
• FlyBaseID: FBgn0003079
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_502160.4
• Gene: F22B3.8 / 184809
• WormBaseID: WBGene00009039
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 318
• Identity: 94/318 - (29%)
• Similarity: 149/318 - (46%)
• Gaps: 63/318 - (19%)

  Fly   420 ENWNILAEEILIGP-RIGSGSFGTVYRAHWHGP-------------VAVKTLNVKTPSPAQLQAF 470
            ::|.:.||.|.:.| ::|.|:||.||...|..|             |||||:. ...|.|.|...
 Worm   202 QDWELRAEGIDMTPKKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVK-NDDSRAALLEV 265

  Fly   471 KNEVAMLKKTRHCNILLFMG--CVSKPSLAIVTQWCEGSSLYKHVHVSE-TKFKLNTLIDIGRQV 532
            .:|..:..:.||.|:|.|.|  .:.|| :.:|:::||.......|.|.| .:|.|.:
 Worm   266 MHEARLQLQLRHKNVLAFRGVFLLKKP-IMLVSEFCENYLQKSKVSVDEKLRFCLGS-------- 321

  Fly   533 AQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVI 597
            :.|::|:|.|.:|||||.:.||.:..|.:.||.|||||...:.:...|....|   :.::|||.:
 Worm   322 SCGLEYIHFKGLIHRDLATRNILVSADKTPKIADFGLAKHASSYKMRKATKIP---VRYLAPETL 383

  Fly   598 RMQELNPYSFQSDVYAFGIVMYELLA-------------ECLPYGHISNKDQILFMVGRG----- 644
               ....||.::|||.||:|::|:.|             ||     ::.|:..|    ||
 Worm   384 ---SSFVYSTKTDVYTFGLVIWEIFANGQEPYMKAQPHQEC-----VAPKNTQL----RGRHIKE 436

  Fly   645 LLRPDM-SQVRSDAPQALKR-LAEDCIKYTPKDRPLFRPLLNMLENMLRT-LPKIHRS 699
            |:|.:: .:...:||.||:: :|........|.||....:...|.:||:. |.|:..|
 Worm   437 LIRKELFVKFNQEAPVALQQYVAAKLFVVDDKKRPDMPEVSTFLGDMLKVDLTKMRYS 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_001096867.3	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	83/287 (29%)
F22B3.8	NP_502160.4	SH2	64..186	CDD:214585
		S_TKc	216..476	CDD:214567	83/284 (29%)
		PTKc	216..>412	CDD:270623	67/211 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000