DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2854 and tcaim

DIOPT Version :9

Sequence 1:	NP_569999.1	Gene:	CG2854 / 31219	FlyBaseID:	FBgn0040391	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001016864.1	Gene:	tcaim / 549618	XenbaseID:	XB-GENE-1016142	Length:	490	Species:	Xenopus tropicalis

Alignment Length:	507	Identity:	127/507 - (25%)
Similarity:	215/507 - (42%)	Gaps:	66/507 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RRIVDYCRRLLSTDLVTALRPFYQAIRTDGLAHNPAEKRVNEESLRLLCSHLESLTGPSASCLPP 74
            ::.|...|.|...|..|||||||.|:..|....:|.|:.|||.||:.|..:||:|..|......|
Frog    18 QKFVFQARPLSGADAATALRPFYFAVHPDFFGQHPVEREVNENSLKRLNGYLENLQKPGQKSHKP 82

  Fly    75 DGHLEFYIPSGSDESGSRVVS----RLVRVQVD-RSLLDPRAVICQILRSCKLLPKEKEQEQMKR 134
             ..|.||:...:..:.|..:.    |.|...:| |.||   :.:..||.||.|........::
Frog    83 -AQLTFYVRETNTINDSDTIRTTGFRTVHFTLDTRDLL---STVLDILNSCSLSTAHVNTAEV-- 141

  Fly   135 GQEMEKELG-KVLRKEPVR--------ERVRPPQAPVQKNLSALRELFKDAKREHSLEIWM--RQ 188
            |.|.:...| |.....|::        ...:.|:          .||.:..|.|.::..|:  .|
Frog   142 GMESKPHKGTKAAFDRPIKWDKTYYSFTGFKDPE----------EELEQAQKVETTIIPWLENNQ 196

  Fly   189 ALARSQASEVATLRGKIEGIEAALVQLLGIRGTRYDCGCNMERYHNCL---SILKGLSEDPKVAG 250
            :||..:.::...||.::|.::..|...|.:...|:.....:.  |.|.   |:.:.:.::|:.
Frog   197 SLANKKLTKSFPLREELEQLKNELADQLQLSDIRWQRSWGVA--HRCSQLHSLSRLIQQNPET-- 257

  Fly   251 QLGALRNRFVVFAPYTGISLEGDVMLFSGDSPSGWLAFLSEMRLHEE-QLRLVPLYEKALSAVLL 314
             |...:.|.::|...||:|..|.|||.:.|....|......:..:.. :.:|:.|.|: :|.:|.
Frog   258 -LKMAKGRTLLFTEETGMSASGHVMLGTMDVHHQWAKLFERLPSYTYLERKLLHLQER-ISHLLG 320

  Fly   315 GIRIERRRVPEPGCEARAYAGSLRRVIRAVSEHLR-LEDSVQEL--------PASLQDHHLAIVP 370
            ||.|......:|              :..:.|:.| ||....:|        |.||:...:.:..
Frog   321 GIEIVHIEEQQP--------------LLTIEEYYRMLETFYNKLLNNRMPIHPRSLRCLKMILQS 371

  Fly   371 DSDIPKVSQTGLFLAPASCSGPDLVEFICRNLDVASGRFSRYRRDIQVERQLWRQCQEELGLQRL 435
            |...|::.:.|.::.|..|....|..|:..:...|.....|......||::|...|::...|.||
Frog   372 DRFAPRLHEMGHYIIPTLCDPASLQWFLLAHTQQARDNLKRKEELTFVEQELTTVCKDRSSLSRL 436

  Fly   436 SKDDSVTPDKMVMAIRHLLQ-SGVKSCRGLSLHITNYWSVPTDGIVCIPWDF 486
            .|:.|::..:|:...:.|.. ......:|:.|.|::|:||..||.:||||:|
Frog   437 YKEPSISCVQMIDCCKRLAPLEPFPYLKGMHLCISHYYSVLQDGDLCIPWNF 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2854	NP_569999.1	DUF4460	15..117	CDD:291359	35/106 (33%)
CG2854	NP_569999.1	DUF4461	181..486	CDD:291360	75/320 (23%)
tcaim	NP_001016864.1	DUF4460	23..126	CDD:373225	35/106 (33%)
tcaim	NP_001016864.1	DUF4461	187..488	CDD:373226	75/320 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I6492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3782
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D532678at33208
OrthoFinder	1	1.000	-	-		FOG0006588
OrthoInspector	1	1.000	-	-		otm47425
Panther	1	1.100	-	-	O	PTHR31596
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4830
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160