Protein Alignment CG2854 and TCAIM

DIOPT Version :9

• Sequence 1: NP_569999.1
• Gene: CG2854 / 31219
• FlyBaseID: FBgn0040391
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_001269842.1
• Gene: TCAIM / 285343
• HGNCID: 25241
• Length: 496
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 129/512 - (25%)
• Similarity: 217/512 - (42%)
• Gaps: 77/512 - (15%)

  Fly    15 YCRRLLSTDLVTALRPFYQAIRTDGLAHNPAEKRVNEESLRLLCSHLESLTGPSASCLPPDGHLE 79
            :.|.|...:.|.||||||.|:..|....:|.|:.:||.||:.|..:||:|..|....|.|. .|.
Human    23 FSRALSGAEAVNALRPFYFAVHPDFFGQHPVEREINENSLKRLSVYLENLQKPGFKSLKPT-QLT 86

  Fly    80 FYI----PSGSD------ESGSRVVSRLVRVQVDRSLLDPRAVICQILRSCKLLPKEKEQEQMKR 134
            ||:    .|.||      .||.|.|...:..   |.||   :.:..||.||.|
Human    87 FYVRETDQSSSDGQEPFSTSGFRAVKFTLHT---RDLL---STVLYILNSCSL------------ 133

  Fly   135 GQEMEKELGKVLRKEPVRERVRPPQAPVQKNLSALREL-FKD--------AKREHSLEIWM---- 186
            ..|..:.|...:..:|::|..|.|..|::.:.|..... |||        ::.|.:|..|:
Human   134 SVEHIQSLNTNMHTQPLKEAKRMPDRPIKWDKSYYSFTGFKDPDEDLEQVSRVETTLTSWLDNNG 198

  Fly   187 RQALARSQASEVATLRGKIEGIEAALVQLLGIRGTRYDCGCNMERYHNCLSILKGLSEDPKVAGQ 251
            :.|:.:.:.|  ..||.:::.::..|...|.:...|:.....:.  |.| |.|..||   ::|.|
Human   199 KSAVKKLKNS--LPLRKELDRLKDELSHQLQLSDIRWQRSWGIA--HRC-SQLHSLS---RLAQQ 255

  Fly   252 ----LGALRNRFVVFAPYTGISLEGDVMLFSGDSPSGWLAFLSEMRLHEEQLRLVPLYEKALSAV 312
                |...:...::|...:|:|..|.|||.:.|....|......:..:.:..|.:.:.|..:|.:
Human   256 NLETLKKAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERLPSYFDLQRRLMILEDQISYL 320

  Fly   313 LLGIRIERRRVPEPGCEARAYAGSLRRVIRAVSEHLRLED---------SVQELPASLQDHHLAI 368
            |.||::             .|...|:.|: .:.|:..|.|         .:...|.||:...:.:
Human   321 LGGIQV-------------VYIEELQPVL-TLEEYYSLLDVFYNRLLKSRILFHPRSLRGLQMIL 371

  Fly   369 VPDSDIPKVSQTGLFLAPASCSGPDLVEFICRNLDVASGRFSRYRRDIQVERQLWRQCQEELGLQ 433
            ..|...|.:.:.|.|..|..|...:|..||......|.....|......:|.:|.:...::..|:
Human   372 NSDRYAPSLHELGHFNIPTLCDPANLQWFILTKAQQARENMKRKEELKVIENELIQASTKKFSLE 436

  Fly   434 RLSKDDSVTPDKMVMAIRHLLQSGVKSCRGLSLHITNYWSVPTDGIVCIPWDFMSRE 490
            :|.|:.|::..:||...:.||:..:....|:.|.|::::||..||.:||||::.:.|
Human   437 KLYKEPSISSIQMVDCCKRLLEQSLPYLHGMHLCISHFYSVMQDGDLCIPWNWKNGE 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2854	NP_569999.1	DUF4460	15..117	CDD:291359	37/111 (33%)
		DUF4461	181..486	CDD:291360	74/321 (23%)
TCAIM	NP_001269842.1	DUF4460	24..128	CDD:317131	37/110 (34%)
		DUF4461	189..489	CDD:317132	74/321 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151011
Domainoid	1	1.000	143	1.000	Domainoid score	I4657
eggNOG	1	0.900	-	-		E1_28KZH
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3619
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47934
OrthoDB	1	1.010	-	-		D532678at33208
OrthoFinder	1	1.000	-	-		FOG0006588
OrthoInspector	1	1.000	-	-		otm40253
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR31596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4830
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.870