Protein Alignment CG2918 and hscA

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_417021.1
• Gene: hscA / 944885
• ECOCYCID: EG12130
• Length: 616
• Species: Escherichia coli
• Alignment Length: 673
• Identity: 146/673 - (21%)
• Similarity: 271/673 - (40%)
• Gaps: 109/673 - (16%)

  Fly    25 VDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAYGYLLD 89
            :|||:....|..|..| ..|...:.|.:...|:::.::....::|.||:|....|..:....:..
E. coli    24 IDLGTTNSLVATVRSG-QAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKR 87

  Fly    90 LLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFRKSDTDEFSVEELVAQLLVKAKQFAQESVQQ 154
            |:|::    :.|: ::|:|:.........|.:...::.....:...:.|.:|......|.|::..
E. coli    88 LMGRS----LADI-QQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAG 147

  Fly   155 PITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHRGEINETAQ--YFLF 217
            .:...|:|||.||..|:|:....||:||.|.||:|:|:..|.|:.||:       ::.|  ....
E. coli   148 ELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGL-------DSGQEGVIAV 205

  Fly   218 YDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALKKTK 282
            ||:|......:::          |....|.:||..|.|..|||.:....|.||:.::.....::.
E. coli   206 YDLGGGTFDISIL----------RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSD 260

  Fly   283 TDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPRATK 347
            .      |...:|...|...|..||........:..      ::..::||:..:|...|..|...
E. coli   261 N------RVQRELLDAAIAAKIALSDADSVTVNVAG------WQGEISREQFNELIAPLVKRTLL 313

  Fly   348 PLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIKQELGKNLNADESATMGAVYKAADLS 412
            ....||..:.:..|.:.:|::.||.||||.|:|.:.....:....:::.|:...:||..: ||:.
E. coli   314 ACRRALKDAGVEADEVLEVVMVGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQ-ADIL 377

  Fly   413 AGFKV-KKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITFNKHTDDFEFY 476
            .|.|. .:.::.|  :.||.:..|.   .|..|::|          .|:...|...:..|...|
E. coli   378 VGNKPDSEMLLLD--VIPLSLGLET---MGGLVEKV----------IPRNTTIPVARAQDFTTF- 426

  Fly   477 VNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKGIKAY----------FYLDD 531
                      |:...|: |::|.:.:.:.|::....::..|   :||.|.          |.:|.
E. coli   427 ----------KDGQTAM-SIHVMQGERELVQDCRSLARFAL---RGIPALPAGGAHIRVTFQVDA 477

  Fly   532 SGIF------RCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQE-EAANA 589
            .|:.      :.||||...: .||.....:....|....::|  :.::..:.:..:||: |||..
E. coli   478 DGLLSVTAMEKSTGVEASIQ-VKPSYGLTDSEIASMIKDSMS--YAEQDVKARMLAEQKVEAARV 539

  Fly   590 GE--------EPSKSEDNEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFV 646
            .|        :.:.....|:...:||: ...||.:...|.:|..:.||.|        :.|||
E. coli   540 LESLHGALAADAALLSAAERQVIDDAA-AHLSEVAQGDDVDAIEQAIKNV--------DKQTQ-- 593

  Fly   647 VPLVGSAYDQSVAKLAAINKAEE 669
             .......||||.:....:..:|
E. coli   594 -DFAARRMDQSVRRALKGHSVDE 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	135/627 (22%)
		HYOU1-like_NBD	23..409	CDD:212672	87/385 (23%)
		TAF4	<572..>627	CDD:296797	13/63 (21%)
hscA	NP_417021.1	hscA	1..616	CDD:235360	146/673 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
	2	1.900