Protein Alignment Grp170 and SSA3

DIOPT Version :10

• Sequence 1: NP_569995.1
• Gene: Grp170 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_009478.1
• Gene: SSA3 / 852203
• SGDID: S000000171
• Length: 649
• Species: Saccharomyces cerevisiae
• Alignment Length: 615
• Identity: 163/615 - (26%)
• Similarity: 285/615 - (46%)
• Gaps: 52/615 - (8%)

  Fly    23 MSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAYGYL 87
            :.:|||:.:..|...| ...:||..|.:..|.||:.:||.|..|.||:.|:.....:|::.....
Yeast     5 VGIDLGTTYSCVAHFS-NDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDA 68

  Fly    88 LDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFRKSDTDEFSVEELVAQLLVKAKQFAQESV 152
            ..|:|:..|:|.|....|.||:..|..|.:....|..|.:|..|:.||:.:.:|.|.|:.|:..:
Yeast    69 KRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYL 133

  Fly   153 QQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHRGEINETAQYFLF 217
            ...:.:.|:|||.||..::|:|...|..:|.:.||::||:..|.|:.||:..:|......   |.
Yeast   134 GTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNV---LI 195

  Fly   218 YDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALKKTK 282
            :|:|......:::|..          ..|.:|.....|..|||.:...||.::||.||.  :|||
Yeast   196 FDLGGGTFDVSLLSID----------EGVFEVKATAGDTHLGGEDFDNRLVNHLATEFK--RKTK 248

  Fly   283 TDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPRATK 347
            .|::.:.|:|.:|...|.|.|..||::::...:|::|.|.:||...:||.:.|:||.||:....:
Yeast   249 KDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLE 313

  Fly   348 PLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIK-QELGKNLNADESATMGAVYKAADL 411
            |:|:.|..|.|....|::::|.||.||:|::|:.:..... :|..:::|.||:...||..:||.|
Yeast   314 PVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAIL 378

  Fly   412 SAGFKVKKFVVKDATLF---PLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITFNKHTDDF 473
            :.....|   .:|..|.   ||.:..|  ...|...|.:.|     .:..|.||..||:.:.|:.
Yeast   379 TGDQSTK---TQDLLLLDVAPLSLGIE--TAGGIMTKLIPR-----NSTIPTKKSETFSTYADNQ 433

  Fly   474 E-FYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKG---IKAYFYLDDSGI 534
            . ..:...:.:|...::...||...::.:....               :|   |...|.:|.:||
Yeast   434 PGVLIQVFEGERTRTKDNNLLGKFELSGIPPAP---------------RGVPQIDVTFDIDANGI 483

  Fly   535 FRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEEPSKSEDN 599
            ...:.:|....|.......::...|||  ..:.::.::..:.:.|:..:.|...|..:.......
Yeast   484 LNVSALEKGTGKSNKITITNDKGRLSK--DDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFT 546

  Fly   600 EKAKEEDAS-KEQKSEESTKQDTEAKNETI 628
            .|....:|| ||:..|:..|:...|..|||
Yeast   547 LKNTINEASFKEKVGEDDAKRLETASQETI 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grp170	NP_569995.1	ASKHA_NBD_HSP70_HYOU1	21..409	CDD:466828	117/386 (30%)
		PTZ00121	<546..917	CDD:173412	18/84 (21%)
		TAF4	<572..>627	CDD:461598	11/55 (20%)
SSA3	NP_009478.1	PTZ00009	4..649	CDD:240227	163/615 (27%)